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亮叶哈勒瑞亚叶和茎甲醇提取物的药用潜力评估。

Evaluation of the medicinal potentials of the methanol extracts of the leaves and stems of Halleria lucida.

作者信息

Adedapo A A, Jimoh F O, Koduru S, Masika P J, Afolayan A J

机构信息

ARDRI, University of Fort Hare, Alice 5700, South Africa.

出版信息

Bioresour Technol. 2008 Jul;99(10):4158-63. doi: 10.1016/j.biortech.2007.08.066. Epub 2008 Jan 28.

Abstract

The medicinal potentials of the methanol extracts of the leaves and stems of Halleria lucida (Scrophulariaceae) were evaluated by assessing their antibacterial and antioxidant properties in vitro using standard procedures. The antioxidant activities of methanol extract of the leaves as determined by the ABTS, DPPH, proanthocyanidins and total flavonoids were higher than that of the stem. On the other hand, the total phenols, the flavonoids and the FRAP contents of the stem were higher than that of the leaves. The extracts however showed poor activity against both Gram-positive and Gram-negative bacteria. The methanol extract of the stem showed activities against Bacillus cereus and Staphylococcus epidermidis at MIC of 1.0 mg/ml. The methanol extract of the leaves did not show activity against any of the organisms used in this study. This study has to some extent validated the medicinal potential of the leaves and stems of H. lucida.

摘要

通过采用标准程序在体外评估其抗菌和抗氧化特性,对光叶哈氏木(玄参科)叶和茎的甲醇提取物的药用潜力进行了评价。通过ABTS、DPPH、原花青素和总黄酮测定的叶甲醇提取物的抗氧化活性高于茎。另一方面,茎的总酚、黄酮和FRAP含量高于叶。然而,提取物对革兰氏阳性菌和革兰氏阴性菌均表现出较弱的活性。茎的甲醇提取物对蜡样芽孢杆菌和表皮葡萄球菌有活性,最低抑菌浓度为1.0mg/ml。叶的甲醇提取物对本研究中使用的任何一种微生物均无活性。本研究在一定程度上验证了光叶哈氏木叶和茎的药用潜力。

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