Malagò Roberto, Manfredi Riccardo, Benini Luigi, D'Alpaos Gianni, Mucelli Roberto Pozzi
Department of Radiology, Policlinico G.B. Rossi, University of Verona, P.le L.A.Scuro, 10, 37134, Verona, Italy.
Abdom Imaging. 2008 Nov-Dec;33(6):669-75. doi: 10.1007/s00261-008-9368-8.
The aim of our study was to evaluate the accuracy of magnetic resonance imaging (MRI) in evaluating Crohn's disease (CD) activity compared to clinical/laboratory data.
Ninety-three consecutive patients with CD were prospectively studied by MR imaging, before and after Gadolinium chelates administration, with use of a biphasic endoluminal contrast agent. MR image analysis included: number of lesions, presence/absence of bowel stenosis, upstream bowel dilation, wall thickness, presence of enhancement, enhancement pattern, presence/absence of comb sign, lymph nodes, and perianal fistulas/abscesses. Clinical evaluation was performed by means of Harvey & Bradshaw Index. Acute-phase reactants were considered standard of reference to monitor biological activity (BA). MR imaging findings were compared with clinical and laboratory data.
MR image analysis detected: In 96 exams multiple lesions in 16, 1 in 50; no lesions in 30; stenosis in 52; dilatation in 28; wall thickening in 59; significant enhancement in 57; layered pattern in 50; comb sign in 37; enlarged lymph nodes in 16; fibro-fatty proliferation in 40; fistulas in 9.
MRI is able to depict morphological changes and is helpful in assessing Crohn's inflammatory disease.
我们研究的目的是评估与临床/实验室数据相比，磁共振成像（MRI）在评估克罗恩病（CD）活动度方面的准确性。
连续93例CD患者在静脉注射钆螯合物前后，使用双相腔内造影剂进行前瞻性磁共振成像研究。磁共振图像分析包括：病变数量、是否存在肠狭窄、上游肠管扩张、肠壁厚度、强化情况、强化方式、是否存在梳征、淋巴结以及肛周瘘管/脓肿。通过哈维&布拉德肖指数进行临床评估。急性期反应物被视为监测生物学活性（BA）的参考标准。将磁共振成像结果与临床和实验室数据进行比较。
磁共振图像分析检测到：在96次检查中，16例有多处病变，50例有1处病变；30例无病变；52例有狭窄；28例有扩张；59例有肠壁增厚；57例有明显强化；50例有分层模式；37例有梳征；16例有肿大淋巴结；40例有纤维脂肪增生；9例有瘘管。
MRI能够描绘形态学变化，有助于评估克罗恩炎性疾病。
