Enns C
Oregon Health Sciences University, Portland, Oregon, USA.
Curr Protoc Cell Biol. 2001 May;Chapter 15:Unit 15.1. doi: 10.1002/0471143030.cb1501s03.
Proteins migrate from the site of their synthesis to intracellular, surface, or extracellular sites depending on their function. This well-illustrated overview provides an introduction to the pathways of protein trafficking. It includes descriptions of the relevant cellular compartments, modifications associated with the movement of proteins through these compartments, signals used for targeting and translocation, mechanisms for transit between compartments, and methods for sorting proteins.
蛋白质根据其功能从合成部位迁移到细胞内、表面或细胞外部位。这一详细阐述的概述介绍了蛋白质运输途径。它包括对相关细胞区室的描述、与蛋白质通过这些区室移动相关的修饰、用于靶向和转运的信号、区室之间转运的机制以及蛋白质分选方法。