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重症肌无力:10 年血浆置换治疗经验

Myasthenia gravis: treatment with plasma exchange experiences over 10 years.

作者信息

Fornádi L, Horváth R, Szobor A

机构信息

Dept. of Neurology, Ferenc Jahn Teaching Hospital, Budapest.

出版信息

Acta Med Hung. 1991;48(3-4):137-44.

PMID:1822852
Abstract

Evaluation of the results of plasmapheresis therapy is reviewed on 160 patients suffering from myasthenia gravis. This new therapeutical procedure is considered very valuable: improvement can be achieved in 63% of the patients during the therapy, a further improvement in 30% after it. Plasmapheresis is especially effective for patients in respiratory crisis-prone state, for drug-resistant cases and for preparation patients for surgery. Plasma exchange therapy may be combined with other forms of immunosuppression with benefit. Thymectomy and plasma exchange are considered to be the main therapeutical procedures in myasthenia gravis.

摘要

对160例重症肌无力患者血浆置换治疗的结果进行了评估。这种新的治疗方法被认为非常有价值:63%的患者在治疗期间病情得到改善,治疗后另有30%的患者病情进一步改善。血浆置换对处于易发生呼吸危象状态的患者、耐药病例以及为手术做准备的患者特别有效。血浆置换疗法可与其他形式的免疫抑制联合使用,效果良好。胸腺切除术和血浆置换被认为是重症肌无力的主要治疗方法。

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