Vicente J, Salvador J, Laguna P, Algaba F
Fundacion Puigvert, Barcelona, Spain.
Eur Urol. 1991;20(3):192-6. doi: 10.1159/000471698.
Based on 3 study groups we have tried to analyze some concepts concerning the treatment of superficial bladder tumors by the Nd-YAG laser. In the first group of 34 superficial bladder tumors, we evaluated the accuracy of cold-cup biopsy in staging the tumor before treatment with the laser (100% for grade and 90% for stage). The possibility of identifying the tumoral grade in the lasered mass is 73%. In the second group of 53 random superficial bladder tumors we compared the effects of laser and transurethral resection (TUR) with regard to recurrence and progression after a 3-year follow-up: no significant differences are found between the treatments. In the third group the histologic changes in the bladder wall after treatment with the laser or TUR were evaluated by cold-cup biopsy (31 lasered cases and 24 resected cases) and by resector loop biopsy (11 lasered cases and 11 resected cases) between 12 and 24 months after treatment, without significant differences in terms of fibrosis.
基于3个研究组，我们试图分析一些关于用钕钇铝石榴石激光治疗浅表膀胱肿瘤的概念。在第一组34例浅表膀胱肿瘤中，我们评估了冷杯活检在激光治疗前对肿瘤分期的准确性（分级准确率为100%，分期准确率为90%）。在激光治疗的肿块中识别肿瘤分级的可能性为73%。在第二组53例随机浅表膀胱肿瘤中，我们比较了激光治疗和经尿道切除术（TUR）在3年随访后的复发和进展情况：两种治疗方法之间未发现显著差异。在第三组中，通过冷杯活检（31例激光治疗病例和24例切除病例）和切除环活检（11例激光治疗病例和11例切除病例）评估了激光治疗或TUR后12至24个月膀胱壁的组织学变化，在纤维化方面没有显著差异。
