Tarantino A E, Aretz H T, Libertino J A, Bihrle W, Dowd J B
Department of Urology, Lahey Clinic Medical Center, Burlington, Massachusetts.
Urology. 1991 Dec;38(6):514-8. doi: 10.1016/0090-4295(91)80167-6.
The neodymium:YAG (yttrium-aluminum-garnet) laser can cause transmural coagulation necrosis of bladder tumor or bladder wall. Pathologic specimens of 18 patients prospectively treated with the neodymium:YAG laser before radical cystectomy were reviewed to compare the initial clinical stage of bladder tumor with the final pathologic stage and to assess the destructive tissue effects of neodymium:YAG laser therapy. Eleven of 18 patients were unchanged pathologically in stage of tumor or had tumor progression. Seven patients had a lower pathologic tumor stage; 3 of these patients had pathologic Stage T0 with no residual tumor, with the remainder of patients showing superficial disease. One asymptomatic small bowel injury was discovered at operation. Healing lesions showed marked granulation tissue, coagulation necrosis, and persistent ulceration.
钇铝石榴石（Nd:YAG）激光可导致膀胱肿瘤或膀胱壁的透壁性凝固性坏死。对18例在根治性膀胱切除术前行钕：钇铝石榴石激光治疗的患者的病理标本进行回顾性分析，以比较膀胱肿瘤的初始临床分期与最终病理分期，并评估钕：钇铝石榴石激光治疗的组织破坏效果。18例患者中，11例肿瘤分期在病理上无变化或有肿瘤进展。7例患者的病理肿瘤分期较低；其中3例患者病理分期为T0，无残留肿瘤，其余患者表现为浅表疾病。术中发现1例无症状的小肠损伤。愈合的病变表现为明显的肉芽组织、凝固性坏死和持续性溃疡。
