将神经可塑性原理转化为言语运动控制恢复与康复研究。
Translating principles of neural plasticity into research on speech motor control recovery and rehabilitation.
作者信息
Ludlow Christy L, Hoit Jeannette, Kent Raymond, Ramig Lorraine O, Shrivastav Rahul, Strand Edythe, Yorkston Kathryn, Sapienza Christine M
机构信息
National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
出版信息
J Speech Lang Hear Res. 2008 Feb;51(1):S240-58. doi: 10.1044/1092-4388(2008/019).
PURPOSE
To review the principles of neural plasticity and make recommendations for research on the neural bases for rehabilitation of neurogenic speech disorders.
METHOD
A working group in speech motor control and disorders developed this report, which examines the potential relevance of basic research on the brain mechanisms involved in neural plasticity and discusses possible similarities and differences for application to speech motor control disorders. The possible involvement of neural plasticity in changes in speech production in normalcy, development, aging, and neurological diseases and disorders was considered. This report focuses on the appropriate use of functional and structural neuroimaging and the design of feasibility studies aimed at understanding how brain mechanisms are altered by environmental manipulations such as training and stimulation and how these changes might enhance the future development of rehabilitative methods for persons with speech motor control disorders.
CONCLUSIONS
Increased collaboration with neuroscientists working in clinical research centers addressing human communication disorders might foster research in this area. It is hoped that this article will encourage future research on speech motor control disorders to address the principles of neural plasticity and their application for rehabilitation.
目的
回顾神经可塑性原理，并为神经源性言语障碍康复的神经基础研究提出建议。
方法
一个言语运动控制与障碍方面的工作组撰写了本报告，该报告审视了关于神经可塑性所涉及的脑机制的基础研究的潜在相关性，并讨论了其应用于言语运动控制障碍时可能存在的异同。考虑了神经可塑性在正常、发育、衰老以及神经疾病和障碍中言语产生变化方面的可能作用。本报告重点关注功能和结构神经影像学的恰当应用以及可行性研究的设计，旨在了解脑机制如何因训练和刺激等环境操作而改变，以及这些变化如何可能促进针对言语运动控制障碍患者的康复方法的未来发展。
结论
与在解决人类交流障碍的临床研究中心工作的神经科学家加强合作，可能会推动该领域的研究。希望本文能鼓励未来针对言语运动控制障碍的研究关注神经可塑性原理及其在康复中的应用。
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