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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Vidotto M C, Furlaneto M C, Perugini M R

Departamento de Patologia Geral, Universidade Estadual de Londrina, Brasil.

Braz J Med Biol Res. 1991;24(4):365-73.

Escherichia coli strains isolated from 100 urine samples taken from patients with urinary tract infections (UTI) and from 20 normal fecal (NF) samples were examined for serum resistance, mannose-resistant hemagglutination of human erythrocytes (MRHA) and for production of aerobactin, hemolysin and colicin. 2. Among the UTI E. coli strains, 79% produced aerobactin, 69% showed serum resistance, 44% produced MRHA, 32% were beta-hemolytic and 22% were colicinogenic. A greater proportion of UTI E. coli strains produced aerobactin, colicin V, beta-hemolysis and MRHA when compared to NF strains. Production of MR hemagglutinins was significantly correlated with that of aerobactin and hemolysin. 3. These results suggest that the presence of aerobactin may be a significant etiological factor in UTI, and that the production of MR adhesins and of hemolysin also might contribute to the virulence of these strains.

对从患有尿路感染（UTI）的患者采集的100份尿液样本以及20份正常粪便（NF）样本中分离出的大肠杆菌菌株进行血清抗性、人红细胞甘露糖抗性血凝（MRHA）以及气杆菌素、溶血素和大肠杆菌素产生情况的检测。2. 在UTI大肠杆菌菌株中，79%产生气杆菌素，69%表现出血清抗性，44%产生MRHA，32%为β溶血，22%产生大肠杆菌素。与NF菌株相比，UTI大肠杆菌菌株产生气杆菌素、大肠杆菌素V、β溶血和MRHA的比例更高。MR血凝素的产生与气杆菌素和溶血素的产生显著相关。3. 这些结果表明，气杆菌素的存在可能是UTI的一个重要病因，并且MR黏附素和溶血素的产生也可能有助于这些菌株的毒力。

Vidotto M C, Furlaneto M C, Perugini M R

Departamento de Patologia Geral, Universidade Estadual de Londrina, Brasil.

Braz J Med Biol Res. 1991;24(4):365-73.

Escherichia coli strains isolated from 100 urine samples taken from patients with urinary tract infections (UTI) and from 20 normal fecal (NF) samples were examined for serum resistance, mannose-resistant hemagglutination of human erythrocytes (MRHA) and for production of aerobactin, hemolysin and colicin. 2. Among the UTI E. coli strains, 79% produced aerobactin, 69% showed serum resistance, 44% produced MRHA, 32% were beta-hemolytic and 22% were colicinogenic. A greater proportion of UTI E. coli strains produced aerobactin, colicin V, beta-hemolysis and MRHA when compared to NF strains. Production of MR hemagglutinins was significantly correlated with that of aerobactin and hemolysin. 3. These results suggest that the presence of aerobactin may be a significant etiological factor in UTI, and that the production of MR adhesins and of hemolysin also might contribute to the virulence of these strains.

对从患有尿路感染（UTI）的患者采集的100份尿液样本以及20份正常粪便（NF）样本中分离出的大肠杆菌菌株进行血清抗性、人红细胞甘露糖抗性血凝（MRHA）以及气杆菌素、溶血素和大肠杆菌素产生情况的检测。2. 在UTI大肠杆菌菌株中，79%产生气杆菌素，69%表现出血清抗性，44%产生MRHA，32%为β溶血，22%产生大肠杆菌素。与NF菌株相比，UTI大肠杆菌菌株产生气杆菌素、大肠杆菌素V、β溶血和MRHA的比例更高。MR血凝素的产生与气杆菌素和溶血素的产生显著相关。3. 这些结果表明，气杆菌素的存在可能是UTI的一个重要病因，并且MR黏附素和溶血素的产生也可能有助于这些菌株的毒力。