烯丙基锡烷的共轭加成反应并伴随三氟甲磺酸酯化反应。

Conjugate addition of allyl stannanes with concomitant triflation.

作者信息

Beaulieu Ellen D, Voss Leah, Trauner Dirk

机构信息

Department of Chemistry, University of California, Berkeley, Berkeley, California 94720-1460, USA.

出版信息

Org Lett. 2008 Mar 6;10(5):869-72. doi: 10.1021/ol702996t. Epub 2008 Jan 31.

DOI:10.1021/ol702996t

PMID:18232702

Abstract

A new method for the conjugate addition of allyltributylstannane with concomitant triflation is described. This reaction works with functionalized enones, enals, enoates, and vinylogous esters. The resulting vinyl triflates can be used for intramolecular Heck reactions to afford the products of 5-exo-trig cyclization.

摘要

描述了一种烯丙基三丁基锡烷共轭加成并伴随三氟甲磺酸酯化的新方法。该反应适用于官能化的烯酮、烯醛、烯酸酯和插烯酯。所得的乙烯基三氟甲磺酸酯可用于分子内Heck反应，以得到5-外向-三取代环化产物。