串联 Ir 催化的烯丙基砜和异构化的烯丙基取代反应。
Tandem Ir-catalyzed allylic substitution reaction of allyl sulfinates and isomerization.
机构信息
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
出版信息
Org Lett. 2010 Feb 19;12(4):800-3. doi: 10.1021/ol902873q.
PMID:20102175
Abstract
An efficient method for the synthesis of trisubstituted vinyl sulfones is reported. Using the Ir(COD)Cl/phosphoramidite ligand (L1)/DBU, trisubstituted vinyl sulfones could be synthesized from allyl sulfinates in high yields as exclusively E isomers.
摘要
本文报道了一种合成三取代乙烯基砜的有效方法。该方法使用Ir(COD)Cl/磷酰胺配体（L1）/DBU，可高收率、立体专一性地得到 E 式构型的三取代乙烯基砜。反应中，砜源为烯丙基磺酸酯。
Zotero 插件