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Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin.姜黄素单羰基类似物的合成及其抗炎活性
Bioorg Med Chem Lett. 2008 Feb 15;18(4):1525-9. doi: 10.1016/j.bmcl.2007.12.068. Epub 2008 Jan 1.
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Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages.姜黄素单羰基类似物的合成及其对 LPS 刺激的 RAW 264.7 巨噬细胞细胞因子释放抑制作用的影响。
Bioorg Med Chem. 2010 Apr 1;18(7):2388-93. doi: 10.1016/j.bmc.2010.03.001. Epub 2010 Mar 6.
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Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages.新型姜黄素单羰基类似物的合成及其对 LPS 刺激的 RAW 264.7 巨噬细胞的抗炎活性评价。
Eur J Med Chem. 2010 Dec;45(12):5773-80. doi: 10.1016/j.ejmech.2010.09.037. Epub 2010 Oct 8.
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A novel synthetic mono-carbonyl analogue of curcumin, A13, exhibits anti-inflammatory effects in vivo by inhibition of inflammatory mediators.一种新型合成姜黄素单羰基类似物 A13，通过抑制炎症介质发挥体内抗炎作用。
Inflammation. 2012 Apr;35(2):594-604. doi: 10.1007/s10753-011-9350-4.
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Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues.姜黄素类似物的合成、晶体结构及抗炎特性
Eur J Med Chem. 2009 Feb;44(2):915-9. doi: 10.1016/j.ejmech.2008.01.031. Epub 2008 Feb 3.
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Inhibition of LPS-induced production of inflammatory factors in the macrophages by mono-carbonyl analogues of curcumin.姜黄素单羰基类似物对脂多糖诱导的巨噬细胞炎症因子产生的抑制作用。
J Cell Mol Med. 2009 Sep;13(9B):3370-9. doi: 10.1111/j.1582-4934.2009.00711.x. Epub 2009 Feb 20.
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BDMC33, A curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways.姜黄素衍生物BDMC33在巨噬细胞样细胞系统中抑制炎症反应：对NF-κB和MAPK信号通路的抑制作用
Int J Mol Sci. 2012;13(3):2985-3008. doi: 10.3390/ijms13032985. Epub 2012 Mar 6.
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Discovery and evaluation of piperid-4-one-containing mono-carbonyl analogs of curcumin as anti-inflammatory agents.发现和评价姜黄素中单羰基类似物哌啶-4-酮作为抗炎剂。
Bioorg Med Chem. 2013 Jun 1;21(11):3058-65. doi: 10.1016/j.bmc.2013.03.057. Epub 2013 Mar 30.
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Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model.新型姜黄素类似物作为抗炎剂用于预防和治疗小鼠脓毒症模型的合成及生物学评价
Drug Des Devel Ther. 2015 Mar 18;9:1663-78. doi: 10.2147/DDDT.S75862. eCollection 2015.
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Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin.天然生物活性姜黄素新型抗炎衍生物的发现与评估
Drug Des Devel Ther. 2014 Nov 4;8:2161-71. doi: 10.2147/DDDT.S69914. eCollection 2014.
引用本文的文献
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Bioactive Diarylpentanoids: Insights into the Biological Effects beyond Antitumor Activity and Structure-Activity Relationships.生物活性二芳基戊烷类化合物：除抗肿瘤活性外的生物学效应及构效关系的研究进展
Molecules. 2022 Sep 26;27(19):6340. doi: 10.3390/molecules27196340.
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The Involvement of l-Arginine-Nitric Oxide-cGMP-ATP-Sensitive K Channel Pathway in Antinociception of BBHC, a Novel Diarylpentanoid Analogue, in Mice Model.左旋精氨酸-一氧化氮-cGMP-ATP 敏感性钾通道途径参与新型二芳基戊烷类似物 BBHC 在小鼠模型中的抗伤害作用。
Molecules. 2021 Dec 8;26(24):7431. doi: 10.3390/molecules26247431.
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Tailored Functionalization of Natural Phenols to Improve Biological Activity.定制天然酚类化合物的功能化以提高生物活性。
Biomolecules. 2021 Sep 7;11(9):1325. doi: 10.3390/biom11091325.
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5-Bis-(2,6-difluoro-benzylidene) Cyclopentanone Acts as a Selective 11β-Hydroxysteroid Dehydrogenase one Inhibitor to Treat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice.5-双-（2,6-二氟亚苄基）环戊酮作为一种选择性11β-羟基类固醇脱氢酶1抑制剂用于治疗小鼠饮食诱导的非酒精性脂肪性肝病。
Front Pharmacol. 2021 Apr 12;12:594437. doi: 10.3389/fphar.2021.594437. eCollection 2021.
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In-Vitro and In-Silico Evaluations of Heterocyclic-Containing Diarylpentanoids as Bcl-2 Inhibitors Against LoVo Colorectal Cancer Cells.杂环二芳基戊烷类化合物作为 Bcl-2 抑制剂对 LoVo 结肠癌细胞的体外和计算机评估。
Molecules. 2020 Aug 26;25(17):3877. doi: 10.3390/molecules25173877.
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Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells.适当取代的环状双-(2-溴亚苄基)化合物表现为 p300/CARM1 的双重抑制剂，并在癌细胞中诱导细胞凋亡。
Molecules. 2020 Jul 8;25(14):3122. doi: 10.3390/molecules25143122.
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Efficacy and safety of combination of curcuminoid complex and diclofenac versus diclofenac in knee osteoarthritis: A randomized trial.姜黄素复合物与双氯芬酸联合用药对比双氯芬酸治疗膝骨关节炎的疗效与安全性：一项随机试验
Medicine (Baltimore). 2020 Apr;99(16):e19723. doi: 10.1097/MD.0000000000019723.
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Reinforcement of Polycaprolactone/Chitosan with Nanoclay and Controlled Release of Curcumin for Wound Dressing.纳米黏土增强聚己内酯/壳聚糖及其姜黄素控释用于伤口敷料
ACS Omega. 2019 Dec 19;4(27):22292-22301. doi: 10.1021/acsomega.9b02217. eCollection 2019 Dec 31.
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B14 ameliorates bone cancer pain through downregulating spinal interleukin-1β via suppressing neuron JAK2/STAT3 pathway.B14 通过抑制神经元 JAK2/STAT3 通路下调脊髓白细胞介素-1β缓解癌性骨痛。
Mol Pain. 2019 Jan-Dec;15:1744806919886498. doi: 10.1177/1744806919886498.
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Anti-Edematogenic and Anti-Granuloma Activity of a Synthetic Curcuminoid Analog, 5-(3,4-Dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one, in Mouse Models of Inflammation.一种合成姜黄素类似物，5-(3,4-二羟基苯基)-3-羟基-1-(2-羟基苯基)戊-2,4-二烯-1-酮，在炎症的小鼠模型中的抗水肿和抗肉芽肿活性。
Molecules. 2019 Jul 18;24(14):2614. doi: 10.3390/molecules24142614.
本文引用的文献
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Anti-inflammatory drugs in the 21st century.21世纪的抗炎药物。
Subcell Biochem. 2007;42:3-27. doi: 10.1007/1-4020-5688-5_1.
2
Pharmacokinetics and pharmacodynamics of curcumin.姜黄素的药代动力学和药效学
Adv Exp Med Biol. 2007;595:453-70. doi: 10.1007/978-0-387-46401-5_20.
3
Immunomodulation by curcumin.姜黄素的免疫调节作用。
Adv Exp Med Biol. 2007;595:321-41. doi: 10.1007/978-0-387-46401-5_14.
4
Regulation of COX and LOX by curcumin.姜黄素对环氧化酶和脂氧合酶的调节作用。
Adv Exp Med Biol. 2007;595:213-26. doi: 10.1007/978-0-387-46401-5_9.
5
Antioxidant and anti-inflammatory properties of curcumin.姜黄素的抗氧化和抗炎特性。
Adv Exp Med Biol. 2007;595:105-25. doi: 10.1007/978-0-387-46401-5_3.
6
Curcumin: the Indian solid gold.姜黄素：印度的固体黄金。
Adv Exp Med Biol. 2007;595:1-75. doi: 10.1007/978-0-387-46401-5_1.
7
Inflammatory mechanisms of diabetic complications.糖尿病并发症的炎症机制
Curr Diab Rep. 2007 Jun;7(3):242-8. doi: 10.1007/s11892-007-0038-y.
8
HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR.HIV蛋白酶抑制剂增加巨噬细胞中肿瘤坏死因子-α和白细胞介素-6的表达：RNA结合蛋白HuR的作用。
Atherosclerosis. 2007 Nov;195(1):e134-43. doi: 10.1016/j.atherosclerosis.2007.04.008. Epub 2007 May 24.
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Obesity, inflammation, and insulin resistance.肥胖、炎症与胰岛素抵抗。
Gastroenterology. 2007 May;132(6):2169-80. doi: 10.1053/j.gastro.2007.03.059.
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Effects of curcumin on retinal oxidative stress and inflammation in diabetes.姜黄素对糖尿病视网膜氧化应激和炎症的影响。
Nutr Metab (Lond). 2007 Apr 16;4:8. doi: 10.1186/1743-7075-4-8.
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