近期感染个体中用于检测人类免疫缺陷病毒特异性抗体的快速检测方法评估。
Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals.
作者信息
Louie Brian, Wong Ernest, Klausner Jeffrey D, Liska Sally, Hecht Frederick, Dowling Terri, Obeso Martha, Phillips Susan S, Pandori Mark W
机构信息
San Francisco Department of Public Health, 101 Grove St., Room 412, San Francisco, CA 94102, USA.
出版信息
J Clin Microbiol. 2008 Apr;46(4):1494-7. doi: 10.1128/JCM.01945-07. Epub 2008 Jan 30.
Abstract
We have evaluated four current Food and Drug Administration-cleared rapid tests for human immunodeficiency virus (HIV)-specific antibodies with a panel of specimens from recently infected individuals. Recent infection was detected by RNA-based screening coupled with enzyme immunoassay-based testing. We found that the sensitivities of the various rapid tests vary greatly with regard to their ability to detect HIV-specific antibodies in recently infected individuals.
摘要
我们使用一组来自近期感染个体的样本，对目前美国食品药品监督管理局批准的四种检测人类免疫缺陷病毒（HIV）特异性抗体的快速检测方法进行了评估。通过基于RNA的筛查结合基于酶免疫测定的检测来检测近期感染情况。我们发现，各种快速检测方法在检测近期感染个体中HIV特异性抗体的能力方面差异很大。
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