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腰椎融合术后相邻节段活动度增加:与术后5年该节段的进行性退变无关。

Adjacent segment hypermobility after lumbar spine fusion: no association with progressive degeneration of the segment 5 years after surgery.

作者信息

Axelsson Paul, Johnsson Ragnar, Strömqvist Björn

机构信息

Department of Orthopedics, Lund University Hospital, Lund, Sweden.

出版信息

Acta Orthop. 2007 Dec;78(6):834-9. doi: 10.1080/17453670710014635.

Abstract

BACKGROUND AND PURPOSE

Increased intradiscal pressure and relative segmental hypermobility are in vitro observations supporting the idea of increased postoperative load being a reason for progressive degeneration of the free mobile segment adjacent to a lumbar fusion. These mechanisms have been difficult to confirm in clinical studies, and an alternative theory claims instead that the adjacent segment degeneration follows a natural degenerative course in patients who are predisposed. We examined 9 patients 5 years after lumbar fusion, to assess whether relative hypermobility of the segment adjacent to fusion could be correlated to progressive degeneration of the same segment.

PATIENTS AND METHODS

The 9 patients, all of whom had been treated with a lumbar fusion after a preoperative intervertebral mobility assessment by spinal RSA, were re-examined 5 years after surgery. The intervertebral translations of the vertebra proximal to the fusion were determined by RSA and compared to the mobility of the same lumbar segment before fusion. The disc height and any progressive reduction at the two levels proximal to the one fused were measured on conventional radiographs.

RESULTS

Adjacent segment mobility 5 years after fusion--expressed as mean transverse, vertical, and sagittal translation of the vertebra proximal to fusion--was not significantly changed compared to the mobility measured before surgery. Increased mobility of the segment seen in 5 individual patients was not associated with progressive degeneration of the same segment or to a poor clinical outcome.

INTERPRETATION

Hypermobility of the segment adjacent to fusion is not a general finding. Increased mobility that can be seen in certain individuals does not impair the 5-year result. The significance of mechanical alterations in adjacent segment degeneration is uncertain, and it is possibly overestimated.

摘要

背景与目的

椎间盘内压力升高和节段性相对活动度增加是体外观察结果,支持术后负荷增加是腰椎融合相邻活动节段进行性退变原因的观点。这些机制在临床研究中难以证实,另一种理论则认为,相邻节段退变在易患患者中遵循自然退变过程。我们对9例腰椎融合术后5年的患者进行了检查,以评估融合相邻节段的相对活动度增加是否与同一节段的进行性退变相关。

患者与方法

这9例患者术前均通过脊柱RSA进行椎间活动度评估,之后接受了腰椎融合治疗,并在术后5年进行复查。通过RSA测定融合近端椎体的椎间移位,并与融合前同一腰椎节段的活动度进行比较。在传统X线片上测量融合节段近端两个节段的椎间盘高度及任何进行性减小情况。

结果

融合术后5年的相邻节段活动度——以融合近端椎体的平均横向、纵向和矢状面移位表示——与手术前测量的活动度相比无显著变化。5例患者中观察到的节段活动度增加与同一节段的进行性退变或不良临床结局无关。

解读

融合相邻节段活动度增加并非普遍现象。在某些个体中可见的活动度增加并不影响5年的结果。相邻节段退变中机械性改变的意义尚不确定,可能被高估了。

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