Lee-Wong Mary, Collins Jennifer S, Nozad Cyrus, Resnick David J
Beth Israel Medical Center, the Albert Einstein College of Medicine, New York, NY, USA.
Obstet Gynecol. 2008 Feb;111(2 Pt 2):538-9. doi: 10.1097/01.AOG.0000285480.15136.d1.
Human seminal plasma hypersensitivity is a rare disorder that is often misdiagnosed. While this disorder is well described in the allergy and immunology literature, few cases exist in the gynecologic literature.
A young woman presented to our allergy clinic with recurrent vaginal burning, swelling, and itching occurring approximately 10 minutes postcoitally. Semen allergy was suspected. Using her partner's semen, intradermal testing produced 1.6-cm wheal and 6.0-cm flare. The patient underwent intravaginal desensitization, and she and her partner were instructed to have intercourse every 48 hours to maintain desensitization. At 5-month follow-up, they were practicing coitus interruptus with success.
Human seminal plasma hypersensitivity may mimic chronic vaginitis. The intravaginal graded challenge, a form of immunotherapy used by allergists, remains a mainstay in treatment, but is only effective if maintained correctly.
人类精浆过敏是一种罕见疾病，常被误诊。虽然该疾病在过敏和免疫学文献中有充分描述，但在妇科文献中病例较少。
一名年轻女性因性交后约10分钟反复出现阴道烧灼感、肿胀和瘙痒前来我们的过敏诊所就诊。怀疑为精液过敏。使用其伴侣的精液进行皮内试验，出现了1.6厘米的风团和6.0厘米的红晕。患者接受了阴道内脱敏治疗，并指导她和她的伴侣每48小时进行一次性交以维持脱敏状态。在5个月的随访中，他们采用体外射精法并取得了成功。
人类精浆过敏可能类似慢性阴道炎。阴道内分级激发试验是过敏科医生使用的一种免疫疗法，仍然是治疗的主要手段，但只有正确维持才有效。
