Juillerat Pascal, Froehlich Florian, Felley Christian, Pittet Valérie, Mottet Christian, Gonvers Jean-Jacques, Michetti Pierre, Vader John-Paul
Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.
Digestion. 2007;76(2):84-91. doi: 10.1159/000111021. Epub 2008 Feb 7.
Building on the first European Panel on the Appropriateness of Crohn's Disease Treatment (EPACT I) which was held in Lausanne at the beginning of March 2004, a new panel will be convened in Switzerland (EPACT II, November to December 2007) to update this work. A combined evidence- and panel-based method (RAND) will be applied to assess the appropriateness of therapy for Crohn's disease (CD). In preparation for the meeting of experts, reviews of evidence-based literature were prepared for major clinical presentations of CD. During the meeting, an international multidis- ciplinary panel that includes gastroenterologists, surgeons and general practitioners weigh the strength of evidence and apply their clinical experience when assessing the appropriateness of therapy for 569 specific indications (clinical scenarios). This chapter describes in detail the process of updating the literature review and the systematic approach of the RAND Appropriateness Method used during the expert panel meeting.
在2004年3月初于洛桑举行的第一届欧洲克罗恩病治疗适宜性小组会议（EPACT I）的基础上，一个新的小组将于瑞士召开会议（EPACT II，2007年11月至12月），以更新这项工作。将应用一种基于证据和小组的联合方法（兰德方法）来评估克罗恩病（CD）治疗的适宜性。为专家会议做准备，针对CD的主要临床表现编写了循证文献综述。会议期间，一个由胃肠病学家、外科医生和全科医生组成的国际多学科小组在评估569种特定指征（临床情况）的治疗适宜性时，权衡证据的力度并运用他们的临床经验。本章详细描述了更新文献综述的过程以及专家小组会议期间使用的兰德适宜性方法的系统方法。
