Mariańska B, Apel D, Maj S
Klinika Hematologiczna Instytutu Hematologii, Warszawa.
Acta Haematol Pol. 1991;22(1):54-7.
The activity of alkaline phosphatase and peroxidase was measured in polymorphonuclears in 20 cases of myelodysplasia syndromes, 10 cases of chronic myeloid leukaemia. Reduced phosphatase activity was found in 5 cases and peroxidase activity in 3 cases of myelodysplasia syndromes. No evident correlation was noted between the activity of these enzymes and prognosis. Increased proportion of peroxidase-negative granulocytes was observed, moreover, in most cases of chronic myeloid leukaemia. The observations will be continued in larger material.
对20例骨髓增生异常综合征患者及10例慢性髓性白血病患者的多形核细胞中的碱性磷酸酶和过氧化物酶活性进行了测定。在5例骨髓增生异常综合征患者中发现磷酸酶活性降低,3例患者过氧化物酶活性降低。这些酶的活性与预后之间未发现明显相关性。此外,在大多数慢性髓性白血病病例中观察到过氧化物酶阴性粒细胞比例增加。将在更大规模的样本中继续进行观察。