对经无效抗生素治疗后获得的沙眼衣原体临床分离株中的抗生素耐药标志物进行分析。
Analysis of antibiotic resistance markers in Chlamydia trachomatis clinical isolates obtained after ineffective antibiotic therapy.
作者信息
Shkarupeta M M, Lazarev V N, Akopian T A, Afrikanova T S, Govorun V M
机构信息
Institute of Physicochemical Medicine, Federal Agency for Health Care and Social Development, Moscow.
出版信息
Bull Exp Biol Med. 2007 Jun;143(6):713-7. doi: 10.1007/s10517-007-0221-9.
PMID:18239808
Abstract
Antibiotic resistance markers were analyzed in C. trachomatis clinical isolates obtained after ineffective therapy of urogenital chlamydiasis with fluoroquinolones and macrolides. Heterotypical resistance to fluoroquinolones and macrolides was detected in all clinical isolates. No significant mutations in the target genes were detected.
摘要
对经氟喹诺酮类和大环内酯类药物治疗无效的泌尿生殖系统沙眼衣原体临床分离株进行了抗生素耐药性标志物分析。在所有临床分离株中均检测到对氟喹诺酮类和大环内酯类药物的异型耐药。未在靶基因中检测到显著突变。
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