Csendes A, Becker P, Valenzuela J, Braghetto I, Csendes P
Departamento de Cirugía, Hospital Clínico de la Universidad de Chile, Santiago.
Rev Med Chil. 1991 Jan;119(1):38-44.
The incidence and clinical characteristics of multiple or giant ulcers (over 20 mm for duodenal ulcer or 25 mm for gastric ulcer) was evaluated among 1434 patients with peptic ulcers. For gastric ulcers, multiple and giant lesions were found in 27% and 14% of patients respectively. Among duodenal ulcers the corresponding figure were 16% and 2.4%. Patients with triple gastric ulcers have a greater incidence of massive bleeding. Patients with triple duodenal ulcers are older, have more massive bleeding and have a greater incidence of gastric retention and hypersecretion when compared to patients with single or double duodenal ulcers. Giant gastric ulcer was associated to a shorter history and more massive bleeding; giant duodenal ulcer was associated to older age, more massive bleeding and gastric retention, when compared to patients with common size ulcers.
在1434例消化性溃疡患者中评估了多发性或巨大溃疡(十二指肠溃疡直径超过20mm或胃溃疡直径超过25mm)的发生率及临床特征。对于胃溃疡,分别在27%和14%的患者中发现多发性和巨大性病变。十二指肠溃疡患者中相应比例分别为16%和2.4%。患有三处胃溃疡的患者大出血发生率更高。与患有单处或两处十二指肠溃疡的患者相比,患有三处十二指肠溃疡的患者年龄更大,大出血更多,胃潴留和胃酸分泌过多的发生率更高。与普通大小溃疡的患者相比,巨大胃溃疡的病史较短且大出血更多;巨大十二指肠溃疡与年龄较大、大出血及胃潴留有关。