Chang-Chien C S, Wu C S, Chen P C, Lin D Y, Chu C M, Fang K M, Sheen I S, Liaw Y F
Division of Gastroenterology, Chang Gung Memorial Hospital, Lin Kou Medical Center, China.
Dig Dis Sci. 1988 Apr;33(4):400-4. doi: 10.1007/BF01536021.
A prospective study was conducted to evaluate the prognostic value of stigmata of recent hemorrhage in patients with bleeding peptic ulcer. Of 193 patients suffering from peptic ulcer bleeding identified by emergency gastrointestinoscopy, 52 patients were found to have bleeding gastric ulcer (spurt 5, active oozing 9, fresh clot 11, black clot 17, protruding vessel 4, and clear base without stigmata 6); the other 141 had bleeding duodenal ulcer (spurt 5, active oozing 26, fresh clot 43, black clot 23, protruding vessel 15, and clear base without stigmata 31). Patient with continuous bleeding or rebleeding was grouped as unstable bleeders. The rate of unstable bleeders was 39.1% (continuous bleeding 23.9% and rebleeding 15.2%) in patients with gastric ulcer, compared to 9.0% (4.5% and 4.5%) in duodenal ulcer (P less than 0.001). The unstable bleeder rate of ulcers with spurt, active oozing, clot, and protruding vessel was 80%, 44%, 35.7%, and 0%, respectively, in patients with bleeding gastric ulcer; and 33.3%, 19.2%, 6%, and 0%, respectively, in patients with bleeding duodenal ulcer. The data suggest that the stigmata of recent hemorrhage, excluding protruding vessel, has prognostic significance in bleeding gastric ulcer but less in bleeding duodenal ulcer.
开展了一项前瞻性研究,以评估近期出血征象对消化性溃疡出血患者的预后价值。在193例经急诊胃镜检查确诊为消化性溃疡出血的患者中,发现52例为胃溃疡出血(喷射状出血5例、活动性渗血9例、新鲜血凝块11例、黑色血凝块17例、血管突出4例、基底清晰无出血征象6例);另外141例为十二指肠溃疡出血(喷射状出血5例、活动性渗血26例、新鲜血凝块43例、黑色血凝块23例、血管突出15例、基底清晰无出血征象31例)。持续出血或再出血的患者被归为不稳定出血者。胃溃疡患者中不稳定出血者的比例为39.1%(持续出血23.9%,再出血15.2%),而十二指肠溃疡患者中这一比例为9.0%(4.5%和4.5%)(P<0.001)。胃溃疡出血患者中,有喷射状出血、活动性渗血、血凝块和血管突出的溃疡,其不稳定出血率分别为80%、44%、35.7%和0%;十二指肠溃疡出血患者中,上述比例分别为33.3%、19.2%、6%和0%。数据表明,除血管突出外,近期出血征象对胃溃疡出血有预后意义,对十二指肠溃疡出血的预后意义较小。