Li Tao, Qin Lun-xiu, Pan Qi, Pang Jin-zhong, Wang Lu, Sun Hui-chuan, Ye Qing-hai, Fan Jia, Tang Zhao-you
Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Zhonghua Wai Ke Za Zhi. 2007 Oct 1;45(19):1335-7.
To discuss the diagnosis and treatment of primary hepatic carcinoid tumor (PHCT).
Report one case of huge PHCT treated in February 2004, and search the other 19 cases which were published from January 1994 to December 2006 in the Chinese biological and medical literature database. The clinical manifestation, pathological findings, diagnosis and treatment of these 20 PHCT patients were analyzed retrospectively.
The main symptoms were abdominal pain or discomfort (8 cases) and abdominal mass (7 cases), cases with typical carcinoid syndrome were rare (3 cases). Immunohistochemical staining was positive for neuron-specific enolase, chromogranin A and synaptophysin in most cases. Sixteen cases received operation, among which there were 13 removed completely, other 4 cases were treated by transcatheter arterial chemoembolization (TACE).
The definite diagnosis of PHCT depends on pathological and histochemical findings. Complete surgical resection is the best treatment for PHCT with favourable prognosis. TACE is also effective for nonoperative cases.
探讨原发性肝类癌（PHCT）的诊断与治疗。
报告2004年2月收治的1例巨大PHCT病例，并检索1994年1月至2006年12月在中国生物医学文献数据库中发表的其他19例病例。对这20例PHCT患者的临床表现、病理结果、诊断及治疗进行回顾性分析。
主要症状为腹痛或不适（8例）及腹部肿块（7例），典型类癌综合征病例少见（3例）。多数病例神经元特异性烯醇化酶、嗜铬粒蛋白A和突触素免疫组化染色呈阳性。16例接受手术治疗，其中13例完整切除，另外4例采用经导管动脉化疗栓塞术（TACE）治疗。
PHCT的明确诊断依赖于病理及组织化学检查结果。完整手术切除是PHCT的最佳治疗方法，预后良好。TACE对非手术病例也有效。
