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双心室流出道重建策略:Rastelli手术、REV手术还是Nikaidoh手术?

Strategy for biventricular outflow tract reconstruction: Rastelli, REV, or Nikaidoh procedure?

作者信息

Hu Sheng-Shou, Liu Zhi-Gang, Li Shou-Jun, Shen Xiang-dong, Wang Xu, Liu Jin-ping, Yan Fu-Xia, Wang Li-qing, Li Yong-qing

机构信息

Department of Pediatric Cardiovascular Surgery, The National Cardiovascular Institute and Fu Wai Hospital Beijing, Chinese Academy of Medical Science, Beijing, China.

出版信息

J Thorac Cardiovasc Surg. 2008 Feb;135(2):331-8. doi: 10.1016/j.jtcvs.2007.09.060. Epub 2008 Jan 11.

Abstract

OBJECTIVE

Three techniques have been developed as the surgical management for patients with anomalies of ventriculoarterial connection, ventricular septal defect, and pulmonary outflow tract obstruction (stenosis): the Rastelli, Lecompte, (REV), and Nikaidoh procedures. This study was designed to compare these procedures in terms of hemodynamics of the reconstructed biventricular outflow tract, early clinical consequences, and follow-up.

METHODS

Between March 2004 and September 2006, a total of 30 consecutive patients underwent double root translocation procedures (modified Nikaidoh n = 11, REV n = 7, Rastelli n = 12). In the Nikaidoh procedure, both aortic and pulmonary roots were translocated. A single-valved bovine jugular vein patch was used to repair the stenotic pulmonary artery in both Nikaidoh and REV procedures. The Senning procedure was added for those with atrioventricular discordance.

RESULTS

The Nikaidoh procedure was the most time-consuming in terms of mean cardiopulmonary bypass and aortic crossclamp times. The average mechanical ventilation time was significantly shorter in the Rastelli group (63.3 +/- 89 hours) than that in the Nikaidoh group (188.7 +/- 159 hours, P = .016), but not different from that in the REV group (76.4 +/- 112.5 hours, P = .395). Two patients in the REV group and 1 in the Rastelli group died. There were no in-hospital or late deaths in the Nikaidoh group. Postoperative echocardiography demonstrated physiologic hemodynamics in the left ventricular outflow tract and normal heart function in the Nikaidoh group. Abnormal flow pattern in the left ventricular outflow tract was noted in both REV and Rastelli groups. There were no late deaths or reoperations in any group during follow-up.

CONCLUSION

The modified Nikaidoh procedure is a better surgical option for transposition of the great arteries, ventricular septal defect, and pulmonary stenosis in terms of physiologic cardiac hemodynamics. Its long-term benefits need to be evaluated with a larger number of patients and longer follow-up.

摘要

目的

已开发出三种技术作为心室动脉连接异常、室间隔缺损和肺流出道梗阻(狭窄)患者的手术治疗方法:Rastelli手术、Lecompte(REV)手术和Nikaidoh手术。本研究旨在比较这些手术在重建双心室流出道的血流动力学、早期临床后果和随访方面的差异。

方法

2004年3月至2006年9月期间,共有30例连续患者接受了双根移位手术(改良Nikaidoh手术n = 11例,REV手术n = 7例,Rastelli手术n = 12例)。在Nikaidoh手术中,主动脉和肺动脉根部均进行了移位。在Nikaidoh手术和REV手术中均使用单瓣牛颈静脉补片修复狭窄的肺动脉。对于房室不一致的患者加做Senning手术。

结果

就平均体外循环时间和主动脉阻断时间而言,Nikaidoh手术耗时最长。Rastelli组的平均机械通气时间(63.3±89小时)明显短于Nikaidoh组(188.7±159小时,P = 0.016),但与REV组(76.4±112.5小时,P = 0.395)无差异。REV组有2例患者死亡,Rastelli组有1例患者死亡。Nikaidoh组无院内死亡或晚期死亡病例。术后超声心动图显示Nikaidoh组左心室流出道血流动力学生理状态及心功能正常。REV组和Rastelli组均发现左心室流出道血流模式异常。随访期间任何一组均无晚期死亡或再次手术病例。

结论

就生理性心脏血流动力学而言,改良Nikaidoh手术是治疗大动脉转位、室间隔缺损和肺动脉狭窄的更好手术选择。其长期益处需要通过更多患者和更长时间的随访来评估。

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