Neuerer Felix F, Horlacher Karin, Truyen Uwe, Hartmann Katrin
Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München, München, Germany.
J Feline Med Surg. 2008 Jul;10(3):247-51. doi: 10.1016/j.jfms.2007.12.001. Epub 2008 Feb 20.
In-house tests for the identification of faecal parvovirus antigen are now available. The majority of these are licensed for canine parvovirus only; but anecdotal information suggests that they will detect feline panleukopenia virus (FPV) as well. This prospective study was designed to compare five commercially available test systems. In total, 200 faecal samples from randomly selected healthy cats (148) and cats with diarrhoea (52) were tested and compared with the results of examination by electron microscopy. Ten cats were positive for FPV and all of these had diarrhoea. In-house canine parvovirus tests can be used to detect FPV. All tests were suitable to screen cats for faecal parvovirus excretion (positive predictive values for the Witness Parvo, the Snap Parvo, the SAS Parvo, the Fastest Parvo Strip, and the Speed Parvo were 100.0, 100.0, 57.1, 38.9, and 100%, respectively, negative predictive values for the Witness Parvo, the Snap Parvo, the SAS Parvo, the Fastest Parvo Strip, and the Speed Parvo were 97.4, 97.9, 98.9, 98.4, and 97.4%, respectively). In-house parvovirus tests may be positive up to 2 weeks after vaccination, and therefore, in recently vaccinated cats positive results do not necessarily mean infection.
目前已有用于鉴定粪便细小病毒抗原的内部检测方法。其中大多数仅获许可用于检测犬细小病毒;但有传闻称它们也能检测猫泛白细胞减少症病毒(FPV)。本前瞻性研究旨在比较五种市售检测系统。总共对随机选取的健康猫(148只)和腹泻猫(52只)的200份粪便样本进行了检测,并与电子显微镜检查结果进行了比较。10只猫的FPV呈阳性,且所有这些猫都有腹泻症状。内部犬细小病毒检测方法可用于检测FPV。所有检测方法都适合用于筛查猫的粪便细小病毒排泄情况(Witness Parvo、Snap Parvo、SAS Parvo、Fastest Parvo Strip和Speed Parvo的阳性预测值分别为100.0%、100.0%、57.1%、38.9%和100%,Witness Parvo、Snap Parvo、SAS Parvo、Fastest Parvo Strip和Speed Parvo的阴性预测值分别为97.4%、97.9%、98.9%、98.4%和97.4%)。内部细小病毒检测在接种疫苗后长达2周可能呈阳性,因此,在近期接种过疫苗的猫中,阳性结果不一定意味着感染。