Spriggs Merle, Olsson Craig A, Hall Wayne
Ethics Unit, Murdoch Children's Research Institute, Parkville, Vic., Australia.
Aust N Z J Psychiatry. 2008 Mar;42(3):214-20. doi: 10.1080/00048670701827226.
To suggest ways of testing hypotheses about the impact that information on genetic risk may have on the social stigma of mental disorders and to analyse the implications of these hypotheses for genetic screening for mental disorders.
Literature review and critical analysis and synthesis.
An optimistic view is that information on the genetic risk for mental disorders will reduce blame and social stigma experienced by individuals living with mental disorder. A more pessimists view is that genetic risk information and the use of predictive genetic testing will lead to earlier stigmatization of those at risk of mental disorders. Research is identified that is needed to provide a better understanding of the implications of predictive genetic testing for the stigmatization of different mental health disorders.
It is essential that research on the genetics of mental disorders is accompanied by social science research on the ways in which genetic findings influence the lives of those who are tested.
提出检验关于基因风险信息可能对精神障碍社会污名产生影响的假设的方法,并分析这些假设对精神障碍基因筛查的意义。
文献综述以及批判性分析与综合。
一种乐观的观点认为,关于精神障碍基因风险的信息将减少精神障碍患者所遭受的指责和社会污名。一种更为悲观的观点则认为,基因风险信息以及预测性基因检测的使用将导致对有精神障碍风险者的更早污名化。确定了需要开展研究,以更好地理解预测性基因检测对不同精神健康障碍污名化的影响。
对精神障碍遗传学的研究必须辅以社会科学研究,探讨基因研究结果如何影响被检测者的生活。