Orvieto Raoul, Meltzer Simion, Rabinson Jacob, Gemer Ofer, Anteby Eyal Y, Nahum Ravit
Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel.
Fertil Steril. 2008 Oct;90(4):1297-300. doi: 10.1016/j.fertnstert.2007.10.058. Epub 2008 Feb 4.
To examine whether day 3 LH level or FSH-LH ratio predict IVF outcome, we studied patients with a favorable prognosis a priori undergoing controlled ovarian hyperstimulation (COH) with GnRH agonist (agonist group; n = 131) or antagonist (antagonist group; n = 137). Although LH level could not predict IVF outcome, patients undergoing COH using the GnRH antagonist or agonist protocols with FSH-LH ratios >2 or >3, respectively, achieved significantly lower pregnancy rates (11.1% vs. 27.7% and 8.3% vs. 31.9%, respectively).
为了研究第3天的促黄体生成素（LH）水平或促卵泡生成素-促黄体生成素（FSH-LH）比值是否能预测体外受精（IVF）结局，我们预先研究了预后良好、接受促性腺激素释放激素（GnRH）激动剂（激动剂组；n = 131）或拮抗剂（拮抗剂组；n = 137）进行控制性卵巢刺激（COH）的患者。尽管LH水平不能预测IVF结局，但分别使用GnRH拮抗剂或激动剂方案且FSH-LH比值>2或>3的COH患者，其妊娠率显著降低（分别为11.1%对27.7%和8.3%对31.9%）。
