促性腺激素释放激素激动剂与拮抗剂在卵巢刺激中的应用：子宫内膜容受性的作用
GnRH agonist versus GnRH antagonist in ovarian stimulation: the role of endometrial receptivity.
作者信息
Orvieto Raoul, Meltzer Simion, Rabinson Jacob, Zohav Efraim, Anteby Eyal Y, Nahum Ravit
机构信息
Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel.
出版信息
Fertil Steril. 2008 Oct;90(4):1294-6. doi: 10.1016/j.fertnstert.2007.10.022. Epub 2008 Jan 7.
To examine whether the choice of the GnRH analogues used during controlled ovarian hyperstimulation (COH), may influence endometrial receptivity, we studied 712 IVF cycles, in patients undergoing COH with GnRH agonist or antagonist and with the transfer of at least one top-quality embryo. The GnRH agonist group showed significantly higher endometrial thickness and higher pregnancy rate, suggestive of a higher endometrial receptivity, compared with the GnRH antagonist group.
为了研究在控制性卵巢过度刺激（COH）过程中使用的GnRH类似物的选择是否会影响子宫内膜容受性，我们对712个体外受精（IVF）周期进行了研究，这些患者接受了GnRH激动剂或拮抗剂的COH治疗，并移植了至少一个优质胚胎。与GnRH拮抗剂组相比，GnRH激动剂组的子宫内膜厚度明显更高，妊娠率也更高，提示子宫内膜容受性更高。
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