Green J G, Durham T M
Department of Pathology, Diagnosis and Radiology, University of Nebraska Medical Center College of Dentistry.
Oral Surg Oral Med Oral Pathol. 1991 Jan;71(1):27-30. doi: 10.1016/0030-4220(91)90515-e.
Gingival bleeding in the patient with thrombocytopenia can be a difficult management problem. Primary therapy with platelet transfusions may not be sufficient to control the hemorrhage and adjunctive local therapy may be required. Currently, few local management techniques can effectively control this problem. INSTAT collagen absorbable hemostat can be used as a local adjunct with platelet transfusions and has certain application advantages over topical thrombin and microfibrillar collagen. Two successful techniques of INSTAT application to control gingival hemorrhage in a patient with severe thrombocytopenia in leukemic relapse are described.
血小板减少症患者的牙龈出血可能是一个难以处理的问题。单纯输注血小板进行初始治疗可能不足以控制出血,可能需要辅助局部治疗。目前,很少有局部处理技术能有效控制这一问题。INSTAT 可吸收性胶原蛋白止血剂可用作输注血小板时的局部辅助治疗,与局部用凝血酶和微纤维胶原蛋白相比具有一定的应用优势。本文描述了在白血病复发的严重血小板减少症患者中应用 INSTAT 控制牙龈出血的两种成功技术。