Harris W H, Crothers O D, Moyen B J, Bourne R B
J Bone Joint Surg Am. 1978 Jun;60(4):454-6.
The three topical hemostatic agents--gelatin paste, microfibrillar collagen, and gelatin sponge soaked in thrombin--individually were effective in reducing bleeding from cancellous bone, as tested on the femoral surface of trochanteric osteotomies during total hip replacement. During a three-minute interval, the spontaneous reduction in bleeding in eight control hips to which no agent was applied was 11 per cent. Gelatin paste gave a reduction of 85 per cent; gelatin sponge soaked in thrombin, a reduction of 75 per cent; and microfibrillar collagen, a reduction of 47 per cent. None of these agents interfered with healing of the trochanteric osteotomy.
三种局部止血剂——明胶糊剂、微纤维胶原和浸有凝血酶的明胶海绵，在全髋关节置换术中转子截骨术的股骨表面进行测试时，单独使用均能有效减少松质骨出血。在三分钟的时间间隔内，八个未使用任何药剂的对照髋关节出血的自然减少率为11%。明胶糊剂使出血减少了85%；浸有凝血酶的明胶海绵使出血减少了75%；微纤维胶原使出血减少了47%。这些药剂均未干扰转子截骨术的愈合。
