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SV40转化的蜥蜴细胞未能在自体或同种异体宿主中诱导肿瘤。

Failure to SV40-transformed lizard cells to induce tumors in autogeneic or allogeneic hosts.

作者信息

Michalski F J, Slemmer G, Clark H F

出版信息

Experientia. 1976 Aug 15;32(8):1064-5. doi: 10.1007/BF01933974.

DOI:10.1007/BF01933974
PMID:182525
Abstract

Lizard cells from the tails of geckos were readily morphologically and antigenically transformed in vitro by SV40 virus. Neither autografts of these cells nor allografts of SV40 transformed gecko embryo cells produced tumors in animals under observation for 1 to 3 years.

摘要

来自壁虎尾巴的蜥蜴细胞在体外很容易被SV40病毒进行形态学和抗原性转化。这些细胞的自体移植以及SV40转化的壁虎胚胎细胞的同种异体移植在观察1至3年的动物中均未产生肿瘤。

相似文献

1
Failure to SV40-transformed lizard cells to induce tumors in autogeneic or allogeneic hosts.SV40转化的蜥蜴细胞未能在自体或同种异体宿主中诱导肿瘤。
Experientia. 1976 Aug 15;32(8):1064-5. doi: 10.1007/BF01933974.
2
SV40-induced transformation of cells of the lizard Gekko gecko.猿猴病毒40诱导的壁虎细胞转化
Int J Cancer. 1972 May 15;9(3):599-607. doi: 10.1002/ijc.2910090317.
3
Mitogenic and antimitogenic transforming growth factors secreted by adenovirus 2- and simian virus 40-transformed hamster cells: possible roles in promoting tumorigenesis.腺病毒2型和猿猴病毒40转化的仓鼠细胞分泌的促有丝分裂和抗有丝分裂转化生长因子：在促进肿瘤发生中的可能作用。
Cancer Res. 1987 Aug 1;47(15):4086-92.
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Induction in hamsters of various carcinomas and sarcomas by in-vitro SV40-transformed homologous embryonic skin and subcutaneous tissue cells. Role of target cells in determining tumor morphology.通过体外SV40转化的同源胚胎皮肤和皮下组织细胞在仓鼠中诱导各种癌和肉瘤。靶细胞在确定肿瘤形态中的作用。
Am J Pathol. 1969 Jul;56(1):59-77.
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Character of the tumors developing in young hamsters by the mixed cell transplantation of para-adeno-virus 12 and SV40 tumors-the similarity to the tumors induced by para-adenovirus 7.
Acta Pathol Jpn. 1977 May;27(3):321-9. doi: 10.1111/j.1440-1827.1977.tb00158.x.
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The importance of dose and proliferation of SV40-transformed cells with different oncogenic potentials to the level of tumor immunity.具有不同致癌潜能的SV40转化细胞的剂量和增殖对肿瘤免疫水平的重要性。
Int J Cancer. 1974 Mar 15;13(3):273-85. doi: 10.1002/ijc.2910130302.
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Induction of SV40-tumour immunity by SV40-transformed cells in diffusion chambers.
Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Oct;82B(5):676-86. doi: 10.1111/j.1699-0463.1974.tb00235.x.
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Immunologic manipulation of metastases due to herpesvirus transformed cells.对疱疹病毒转化细胞所致转移灶的免疫调控
Science. 1973 Apr 6;180(4081):79-81. doi: 10.1126/science.180.4081.79.
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Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.病毒转化细胞在裸鼠体内的致瘤性与体外非锚定依赖性生长具有特异性相关性。
Proc Natl Acad Sci U S A. 1975 Nov;72(11):4435-9. doi: 10.1073/pnas.72.11.4435.
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Tumorigenicity of simian virus 40-transformed rat hepatocytes.猿猴病毒40转化的大鼠肝细胞的致瘤性。
Cancer Res. 1981 Jun;41(6):2126-34.

本文引用的文献

1
DETECTION OF SPECIFIC ANTIGEN IN SV40-TRANSFORMED CELLS BY IMMUNOFLUORESCENCE.免疫荧光法检测SV40转化细胞中的特异性抗原
J Exp Med. 1964 Aug 1;120(2):121-8. doi: 10.1084/jem.120.2.121.
2
SV-40 INDUCED PROLIFERATION OF TISSUE CULTURE CELLS OF RABBIT, MOUSE, AND PORCINE ORIGIN.猴空泡病毒40诱导的兔、小鼠和猪源组织培养细胞增殖
Proc Soc Exp Biol Med. 1963 Dec;114:721-7. doi: 10.3181/00379727-114-28780.
3
Adult and embryonic gecko cells in vitro: growth characteristics, infection by rabies, sindbis and polyoma viruses, and transformation by SV40.
体外培养的成年和胚胎壁虎细胞：生长特性、狂犬病病毒、辛德毕斯病毒和多瘤病毒感染以及SV40转化
Proc Soc Exp Biol Med. 1974 Jun;146(2):337-48. doi: 10.3181/00379727-146-38100.
4
SV40-induced transformation of cells of the lizard Gekko gecko.猿猴病毒40诱导的壁虎细胞转化
Int J Cancer. 1972 May 15;9(3):599-607. doi: 10.1002/ijc.2910090317.