Huertas-Ceballos A, Logan S, Bennett C, Macarthur C
EGA Hospital, Neonatal Unit, UCLH, Huntley Street, London, UK WC1E 6DH.
Cochrane Database Syst Rev. 2008 Jan 23(1):CD003014. doi: 10.1002/14651858.CD003014.pub2.
Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. For the majority of such children, no organic cause for their pain can be found on physical examination or investigation. Although most children are managed by reassurance and simple measures, a large range of psychosocial interventions including cognitive and behavioural treatments and family therapy have been recommended.
To determine the effectiveness of psychosocial interventions for recurrent abdominal pain or IBS in school-age children.
The Cochrane Library (CENTRAL) 2006 (Issue 4), MEDLINE (1966 to Dec 2006), EMBASE (1980 to Dec 2006), CINAHL (1982 to Dec 2006), ERIC (1966 to Dec 2006), PsycINFO (1872 to Dec 2006), LILACS (1982 to Dec 2006), SIGLE (1980 to March 2005), and JICST (1985 to 06/2000) were searched with appropriate filters.
Any study in which the majority of participants were school-age children fulfilling standard criteria for RAP (Apley or the Rome II criteria for functional gastrointestinal diseases) , randomly allocated to any psychosocial treatment compared to standard care or waiting list, were selected.
References identified by the searches were independently screened against the inclusion criteria by two reviewers. Data were extracted and analysed using RevMan 4.2.10.
Six randomised trials (including a total of 167 participants) of cognitive behavioural interventions were identified, with data reported in ten papers. Five studies reported statistically significant improvements in pain, measured in a variety of ways, in children randomised to receive interventions based on cognitive behavioural therapy compared to children on wait lists or receiving standard medical care (Duarte 2006; Humphreys 1998; Robins 2005; Sanders 1989; Sanders 1994). The remaining trial (Hicks 2003) included a wider group of children with recurrent pain and too few with only RAP to provide interpretable data.
AUTHORS' CONCLUSIONS: The included trials were small, with methodological weaknesses and a number failed to give appropriate detail regarding numbers of children assessed. In spite of these methodological weaknesses and the clinical heterogeneity, the consistency and magnitude of the effects reported provides some evidence that cognitive behavioural therapy may be a useful intervention for children with recurrent abdominal pain although most children, particularly in primary care, will improve with reassurance and time.
4%至25%的学龄儿童主诉反复出现腹痛(RAP),其严重程度足以干扰日常活动。对于大多数此类儿童,体格检查或检查未发现疼痛的器质性原因。尽管大多数儿童通过安慰和简单措施进行处理,但已推荐了一系列心理社会干预措施,包括认知和行为治疗以及家庭治疗。
确定心理社会干预对学龄儿童反复腹痛或肠易激综合征的有效性。
检索了Cochrane图书馆(CENTRAL)2006年第4期、MEDLINE(1966年至2006年12月)、EMBASE(1980年至2006年12月)、CINAHL(1982年至2006年12月)、ERIC(1966年至2006年12月)、PsycINFO(1872年至2006年12月)、LILACS(1982年至2006年12月)、SIGLE(1980年至2005年3月)和JICST(1985年至2000年6月),并使用了适当的筛选条件。
选择任何一项研究,其中大多数参与者为符合RAP标准(阿普利或功能性胃肠疾病的罗马II标准)的学龄儿童,与标准护理或等待名单相比,随机分配接受任何心理社会治疗。
两名评审员根据纳入标准对检索到的参考文献进行独立筛选。使用RevMan 4.2.10提取和分析数据。
确定了六项认知行为干预的随机试验(共167名参与者),十篇论文报告了相关数据。五项研究报告称,与等待名单上或接受标准医疗护理的儿童相比,随机接受基于认知行为疗法干预的儿童在以多种方式测量的疼痛方面有统计学上的显著改善(杜阿尔特,2006年;汉弗莱斯,1998年;罗宾斯,2005年;桑德斯,1989年;桑德斯,1994年)。其余试验(希克斯,2003年)纳入了一组更广泛的反复疼痛儿童,仅有RAP的儿童太少,无法提供可解释的数据。
纳入的试验规模较小,存在方法学上的弱点,一些试验未能提供关于评估儿童数量的适当详细信息。尽管存在这些方法学上的弱点和临床异质性,但报告的效应的一致性和程度提供了一些证据,表明认知行为疗法可能是治疗反复腹痛儿童的有用干预措施,尽管大多数儿童,尤其是在初级保健中,通过安慰和时间推移会有所改善。