Truneh M
Department of Microbiology and Parsitology, Gonder College of Medical Sciences, Ethiopia.
Ethiop Med J. 1991 Jan;29(1):1-6.
Fifty-eight Staphylococcus aureus strains from Gonder College of Medical Sciences Hospital, (43 isolates from patients and 15 from carriers) and 28 from Debre Tabor Hospital (14 each from patients and carriers), both in northwest Ethiopia, were phage typed in 1988. Eighty-one of the 86 strains were recognized by their phage types. A multiresistant strain of type 29 was frequent among Gonder patients'. This strain was also recovered from the hospital personnel. Other well known multiresistant strains of phage type NT/A994 and 85/A994 were identified among patients from Gonder and phage type 85/A994 was recovered from 5 patients and 4 carriers from Debre Tabor. These findings suggest cross-infection with virulent strains of Staphylococcus aureus in both hospitals. All 86 phage-typed strains were tested for susceptibility to 7 antibiotics. A high frequency of multiple resistance was observed. Double resistance to penicillin and tetracycline was frequent among patients strains from Gonder. Among strains of phage type 85/A994 multiresistance to penicillin, chloramphenicol, tetracycline, streptomycin, erythromycin and oxacillin was found. Strains of phage type 85/A994 and NT/A994 were resistant to mercury. No plasmid DNA was detected in one strain of 85/A994 investigated.
1988年，对来自埃塞俄比亚西北部贡德尔医学院医院的58株金黄色葡萄球菌菌株（43株分离自患者，15株分离自携带者）以及来自德布雷塔博尔医院的28株金黄色葡萄球菌菌株（患者和携带者各14株）进行了噬菌体分型。86株菌株中有81株可通过其噬菌体类型识别。29型多重耐药菌株在贡德尔患者中很常见。该菌株也从医院工作人员中分离得到。贡德尔患者中还鉴定出其他著名的噬菌体类型NT/A994和85/A994的多重耐药菌株，85/A994型从德布雷塔博尔的5名患者和4名携带者中分离得到。这些发现表明两家医院都存在金黄色葡萄球菌强毒株的交叉感染。对所有86株经过噬菌体分型的菌株进行了7种抗生素的敏感性测试。观察到多重耐药的高频率。贡德尔患者菌株中对青霉素和四环素双重耐药很常见。在85/A994型菌株中，发现对青霉素、氯霉素、四环素、链霉素、红霉素和苯唑西林多重耐药。85/A994型和NT/A994型菌株对汞耐药。在所研究的一株85/A994菌株中未检测到质粒DNA。
