Gandjbakhche A H, Bonner R F, Nossal R, Weiss G H
Appl Opt. 1997 Jul 1;36(19):4613-9. doi: 10.1364/ao.36.004613.
By applying a random-walk model for photon migration, we find an exact expression for fluorescent signals emitted from a homogeneous, optically turbid medium containing a single fluorescent mass. In contrast to diffusion-theory-based models, our analysis accounts for multiple photon passages through the fluorophore sites and allows for a variable degree of fluorescent absorptivity. We particularly discuss effects on the amplitudes and phase shifts of frequency-domain fluorescent signals.
通过应用光子迁移的随机游走模型,我们找到了从含有单个荧光物质的均匀光学混浊介质中发射的荧光信号的精确表达式。与基于扩散理论的模型不同,我们的分析考虑了光子多次通过荧光团位点的情况,并允许荧光吸收率可变。我们特别讨论了对频域荧光信号的幅度和相移的影响。