Saglik Yener, Atalar Hakan, Yildiz Yusuf, Basarir Kerem, Gunay Cuneyd
Department of Orthopaedic Surgery and Traumatology, Ankara University School of Medicine, Ankara, Turkey.
Acta Orthop Belg. 2007 Dec;73(6):747-53.
Osteoblastoma is a locally aggressive osteoblastic lesion of bone with rare malignant transformation. We retrospectively evaluated 20 patients who were diagnosed and surgically treated for osteoblastoma in our institution. Their mean age was 22.5 years (range: 10 to 34). The most frequent location was in the posterior elements of the spine, followed by the long bones of the extremities and the talus. Intralesional curettage was the most common modality of treatment; it was used in 11 patients, with a 13% recurrence rate. This series demonstrates that osteoblastoma may be locally aggressive and may recur after removal. Although it is usually treated successfully with curettage, wide excision should be considered along with careful follow-up over the long term owing to the possibility of recurrence or malignant transformation.
骨母细胞瘤是一种具有罕见恶性转化的局部侵袭性骨成骨细胞病变。我们回顾性评估了在我们机构诊断并接受手术治疗的20例骨母细胞瘤患者。他们的平均年龄为22.5岁（范围：10至34岁）。最常见的部位是脊柱后部结构，其次是四肢长骨和距骨。病灶内刮除术是最常见的治疗方式；11例患者采用了该方法，复发率为13%。本系列研究表明，骨母细胞瘤可能具有局部侵袭性，切除后可能复发。虽然通常通过刮除术成功治疗，但由于存在复发或恶性转化的可能性，应考虑广泛切除并进行长期仔细随访。
