Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street Yawkey 6E, Boston, MA, 02114, USA.
Department of Radiology, Centro Hospitalar de São João, Porto, Portugal.
Skeletal Radiol. 2019 Oct;48(10):1623-1628. doi: 10.1007/s00256-019-03197-x. Epub 2019 Mar 8.
Osteoblastoma is a rare, benign primary tumor of bone, accounting for < 1% of all bone tumors. We report the case of a 27-year-old female who developed pain and swelling five and a half years after a clavicular fracture and was subsequently found to have an osteoblastoma arising at the fracture site. This is the first reported case of an osteoblastoma developing after a fracture, although osteoid osteomas, which are histologically indistinguishable from osteoblastomas, have been reported at prior fracture sites. This report demonstrates that secondary neoplasms such as osteoblastomas should be considered in the differential diagnosis for pain at a healed fracture site recurring years after the initial trauma.
骨母细胞瘤是一种罕见的良性骨原发性肿瘤,占所有骨肿瘤的<1%。我们报告了一例 27 岁女性的病例,她在锁骨骨折后五年半出现疼痛和肿胀,随后发现骨折部位发生骨母细胞瘤。这是首例报告的骨折后发生骨母细胞瘤的病例,尽管此前曾有报道称在骨折部位出现组织学上与骨母细胞瘤无法区分的骨样骨瘤。本报告表明,对于初始创伤多年后愈合骨折部位再次出现疼痛,应考虑诸如骨母细胞瘤等继发性肿瘤作为鉴别诊断。