Boyvat F, Aytekin C, Harman A, Sevmiş S, Karakayali H, Haberal M
Department of Radiology, Başkent University Medical Faculty, Ankara, Turkey.
Transplant Proc. 2008 Jan-Feb;40(1):22-6. doi: 10.1016/j.transproceed.2007.12.027.
Hepatic artery stenosis or thrombosis following liver transplant is a potentially life-threatening complication. Successful liver transplant depends on uncompromised hepatic arterial inflow. Early diagnosis and treatment of complications prolong graft survival. Interventional radiologic techniques are frequently used to treat hepatic artery complications. Twenty patients with hepatic artery stenoses (n = 11) or thromboses (n = 9) were included in this study. Eighteen of the 20 patients were successfully treated by stent placement. In 9 patients, early endovascular interventions were performed 1 to 7 days after surgery. Two patients were operated owing to the effects of dissection and bleeding from the hepatic artery. Repeat endovascular interventions were performed 10 times in 6 patients. Follow-up ranged from 5 months to 4.5 years. Nine patients with patent hepatic arteries died during follow-up owing to reasons unrelated to the hepatic artery interventions. In 3 patients, the stents became occluded at 3, 5, and 9 months after surgery but no clinical symptoms were present.
肝移植后肝动脉狭窄或血栓形成是一种潜在的危及生命的并发症。成功的肝移植取决于不受影响的肝动脉血流。并发症的早期诊断和治疗可延长移植物存活时间。介入放射技术常用于治疗肝动脉并发症。本研究纳入了20例肝动脉狭窄(n = 11)或血栓形成(n = 9)的患者。20例患者中有18例通过支架置入成功治疗。9例患者在术后1至7天进行了早期血管内介入治疗。2例患者因肝动脉夹层和出血的影响而接受手术。6例患者重复进行了10次血管内介入治疗。随访时间为5个月至4.5年。9例肝动脉通畅的患者在随访期间因与肝动脉干预无关的原因死亡。3例患者的支架在术后3、5和9个月闭塞,但无临床症状。