Werner G, Buchwald A, Unterberg C, Voth E, Kreuzer H, Wiegand V
Department of Cardiology, University of Göttingen, Germany.
Eur Heart J. 1991 Jan;12(1):24-9. doi: 10.1093/oxfordjournals.eurheartj.a059817.
The results of coronary excimer laser angioplasty were evaluated in 70 patients. Forty-five patients had laser angioplasty of coronary stenoses. Twenty-five patients in a total of 35 attempts had wire-guided laser recanalization of chronic coronary occlusions, resulting in a success rate of 71%. Immediate results in both groups demonstrated the efficacy of this technique without serious side-effects. Stenoses were reduced from 90 +/- 5% to 48 +/- 18% diameter reduction (mean +/- standard deviation) by excimer laser angioplasty. Residual stenosis in recanalized vessels after laser angioplasty was 52 +/- 19%. In slightly more than half of the patients with a residual stenosis greater than 50% after excimer laser angioplasty, subsequent balloon angioplasty was performed for further stenosis reduction. While satisfactory immediate results were achieved by excimer laser angioplasty intermediate follow-up revealed a restenosis rate in the same range as with balloon angioplasty.
对70例患者的冠状动脉准分子激光血管成形术结果进行了评估。45例患者接受了冠状动脉狭窄的激光血管成形术。在总共35次尝试中，25例患者对慢性冠状动脉闭塞进行了导丝引导的激光再通术，成功率为71%。两组的即刻结果均显示了该技术的有效性且无严重副作用。通过准分子激光血管成形术，狭窄程度从直径减少90±5%降至48±18%（平均值±标准差）。激光血管成形术后再通血管的残余狭窄率为52±19%。在准分子激光血管成形术后残余狭窄大于50%的患者中，略超过一半的患者随后进行了球囊血管成形术以进一步减轻狭窄。虽然准分子激光血管成形术取得了令人满意的即刻结果，但中期随访显示再狭窄率与球囊血管成形术相同。
