Kurt Semiha, Kisacik Bunyamin, Kaplan Yuksel, Yildirim Beytullah, Etikan Ilker, Karaer Hatice
Department of Neurology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey.
Eur Neurol. 2008;59(5):253-7. doi: 10.1159/000115639. Epub 2008 Feb 8.
Obesity is defined as a risk factor for carpal tunnel syndrome (CTS). In this study, the presence or absence of recovery in median nerve conduction velocities after weight loss in obese patients was assessed in order to determine whether excess weight or other factors influence the higher prevalence of CTS in obese patients.
Patients with body mass indexes (BMIs) >or=30 were included in the study. CTS symptoms, age, gender, height, body weight, and concomitant diseases were evaluated. Nerve conduction studies (NCS) were obtained on one upper extremity. All patients were included in dietetic programs. Three months later, NCS were repeated and compared with the first NCS.
BMIs were statistically significantly lower on the second visits 3 months later (p = 0.0001). No statistically significant difference was observed in the second NCS of electromyographically diagnosed cases with CTS (p > 0.05).
We expected a recovery in median nerve conduction velocities in patients with CTS after weight loss. In the literature, even in untreated cases with CTS, spontaneous improvements in second NCS have been reported. This finding suggests that factors other than excess body weight may be influential in the higher prevalence of CTS in obese patients. A more detailed, genetic-factor-targeted investigation may prove more beneficial to clarify this issue.
肥胖被定义为腕管综合征(CTS)的一个风险因素。在本研究中,评估肥胖患者体重减轻后正中神经传导速度是否恢复,以确定超重或其他因素是否影响肥胖患者中CTS的较高患病率。
体重指数(BMI)≥30的患者纳入本研究。评估CTS症状、年龄、性别、身高、体重和伴随疾病。对一侧上肢进行神经传导研究(NCS)。所有患者均纳入饮食计划。三个月后,重复进行NCS并与首次NCS进行比较。
三个月后的第二次就诊时,BMI在统计学上显著降低(p = 0.0001)。在肌电图诊断为CTS的病例的第二次NCS中未观察到统计学上的显著差异(p>0.05)。
我们预期体重减轻后CTS患者的正中神经传导速度会恢复。在文献中,即使是未经治疗的CTS病例,也有第二次NCS自发改善的报道。这一发现表明,超重以外的因素可能对肥胖患者中CTS的较高患病率有影响。更详细的、针对遗传因素的调查可能对阐明这个问题更有益。