Mansoor Salman, Siddiqui Maimoona, Mateen Farrukh, Saadat Shoab, Khan Zarak H, Zahid Mehr, Khan Hamza H, Malik Shuja A, Assad Salman
Neurology, Registrar Neurology, Cork University Hospital.
Consultant Neurologist, Department of Neurology, Shifa International Hospital, Islamabad, Pakistan.
Cureus. 2017 Jul 26;9(7):e1519. doi: 10.7759/cureus.1519.
Carpal tunnel syndrome (CTS) is the most common compressive entrapment neuropathy caused by the compression of the median nerve at the wrist space known as the carpal tunnel. The epidemiologic factors related to CTS include genetic, medical, social, vocational, and demographic factors. The common symptoms experienced include pain, paresthesia, and numbness in the median nerve distribution. If left untreated, it can lead to irreversible median nerve damage, causing a loss of hand function. Body mass index (BMI) has been attributed as a risk factor for the development of CTS. We planned to determine the frequency of obesity among CTS patients in the neurophysiology department of a tertiary care center in Islamabad, Pakistan. The survey was designed as a cross-sectional descriptive study from March 2016 to August 2016 using a consecutive nonprobability sampling technique. A total of 112 patients with a mean age of 54 ± 5 years were included in the study. In the study population, 39 patients (35 percent) were males and 73 were females (65 percent). Based on BMI, 74 patients (66 percent) had a normal weight and 38 (34 percent) were obese. The frequency of obesity in our study was 34 percent, excluding the other comorbid conditions, which is quite high. Targeted therapy in those with CTS should also include weight reduction measures because obesity poses a cause-and-effect relationship for both the severity and the pathogenesis of CTS.
腕管综合征(CTS)是最常见的压迫性卡压性神经病,由正中神经在腕部称为腕管的间隙处受压引起。与腕管综合征相关的流行病学因素包括遗传、医学、社会、职业和人口统计学因素。常见症状包括正中神经分布区域的疼痛、感觉异常和麻木。如果不进行治疗,可能会导致正中神经不可逆转的损伤,造成手部功能丧失。体重指数(BMI)被认为是腕管综合征发生的一个危险因素。我们计划确定巴基斯坦伊斯兰堡一家三级医疗中心神经生理学部门中腕管综合征患者的肥胖发生率。该调查设计为2016年3月至2016年8月期间的横断面描述性研究,采用连续非概率抽样技术。共有112名平均年龄为54±5岁的患者纳入研究。在研究人群中,39名患者(35%)为男性,73名(65%)为女性。根据BMI,74名患者(66%)体重正常,38名(34%)肥胖。在排除其他合并症的情况下,我们研究中的肥胖发生率为34%,这一比例相当高。对于腕管综合征患者的靶向治疗还应包括减轻体重的措施,因为肥胖与腕管综合征的严重程度和发病机制都存在因果关系。