Björndahl Lars, Haugen Trine B
Centrum för Andrologi och Sexualmedicin, Kliniken för Endokrinologi, Karolinska Universitetssjukhuset, Huddinge.
Tidsskr Nor Laegeforen. 2008 Jan 31;128(3):320-3.
Semen analysis is an important part of the infertility investigation, but its usefulness as a predictor of fertility is under debate.
The article is based on the authors' experience from andrology laboratories and participation in the WHO's editorial committee for standardization of semen analysis and literature retrieved through non-systematic searches of Medline and PubMed.
There is currently no simple and reliable method to predict the fertility of a man. Most laboratories still use semen analyses that are based on methodology introduced in the 1950s. To allow meaningful comparison of results with previous investigations, results from other laboratories or with reference intervals, it is essential that the methods are standardized and evidence-based. Several studies have shown a correlation between semen variables such as sperm concentration, progressive motility and sperm morphology, and time to pregnancy. The results of semen analysis are often difficult to interpret without patient history and other investigations and do not provide a diagnosis by themselves; they must therefore be interpreted in conjunction with other medical investigations of the couple.
精液分析是不孕症检查的重要组成部分，但其作为生育能力预测指标的有效性仍存在争议。
本文基于作者在男科实验室的经验、参与世界卫生组织精液分析标准化编辑委员会的工作以及通过对Medline和PubMed进行非系统检索获取的文献。
目前尚无简单可靠的方法来预测男性的生育能力。大多数实验室仍采用基于20世纪50年代引入的方法进行精液分析。为了使结果能够与先前的研究、其他实验室的结果或参考区间进行有意义的比较，方法必须标准化且基于证据。多项研究表明，精液参数如精子浓度、前向运动能力和精子形态与受孕时间之间存在相关性。如果没有患者病史和其他检查，精液分析结果往往难以解读，且其本身并不能提供诊断；因此，必须结合对夫妻双方的其他医学检查来解读。
