Capozza G, Krasnoselskaya I A, Papa S, Skulachev V P
Institute of Medical Biochemistry and Chemistry, University of Bari, Italy.
FEBS Lett. 1991 Mar 25;280(2):274-6. doi: 10.1016/0014-5793(91)80310-y.
The inhibition of membrane ATPase from the marine alkalotolerant bacterium Vibrio alginolyticus by DCCD, triphenyltin and venturicidin was studied. DCCD proved to be an irreversible inhibitor, while venturicidin and triphenyltin produced a reversible inhibitory effect. The DCCD-binding proteolipid was identified in the membrane preparations. The effect of the inhibitors on ATPase activity and ATP-dependent Na(+)-transport in V. alginolyticus subcellular vesicles is discussed.
