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结肠镜检查作为检测大肠息肉筛查试验的效用。

The usefulness of colonoscopy as a screening test for detecting colorectal polyps.

作者信息

Kim Dae Han, Lee Seok Young, Choi Kui Sung, Lee Ho Jin, Park Su Cheol, Kim Jin, Han Chul Ju, Kim You Cheoul

机构信息

Division of Gastroenterology, Department of Internal Medicine Korea Institute of Radiological and Medical Sciences, Seoul, Korea.

出版信息

Hepatogastroenterology. 2007 Dec;54(80):2240-2.

PMID:18265641
Abstract

BACKGROUND/AIMS: Colonic polyps are the most common lesions encountered during screening colonoscopy. The purpose of this study is to evaluate the usefulness of colonoscopy to detect colonic polyps in adults.

METHODOLOGY

From January 2003 to September 2005, a total of 4,629 adults underwent colonoscopic screening as a part of a health evaluation program. We analyzed the completed questionnaires, and the colonoscopic and pathologic findings.

RESULTS

Complete colonic evaluation was possible in 4,491 (97.0%) subjects, and 804 (17.9%) had adenomatous polyps, including 153 subjects (3.4%) with advanced adenomas. There were no significant complications such as bowel perforation or massive bleeding requiring transfusion in relation to the procedure. There was a trend toward an increased prevalence of adenomatous polyps with age. Among the subjects with polyps, 72.1% of the subjects had distal polyps and the relative risk for proximal polyp, according to the distal findings, was 5.4 (95% CI: 4.5-6.3) for adenomatous polyp, 5.1 (95% CI 3.6-7.0) for advanced adenoma as compared to the finding of no adenomatous polyp.

CONCLUSIONS

Colonoscopy performed by experienced colonoscopists as a screening test is feasible for detecting subjects with colorectal polyps.

摘要

背景/目的:结肠息肉是结肠镜筛查中最常见的病变。本研究旨在评估结肠镜检查在检测成人结肠息肉方面的实用性。

方法

2003年1月至2005年9月,共有4629名成年人作为健康评估项目的一部分接受了结肠镜筛查。我们分析了完整的问卷以及结肠镜和病理检查结果。

结果

4491名(97.0%)受试者完成了全结肠评估,其中804名(17.9%)患有腺瘤性息肉,包括153名(3.4%)患有进展性腺瘤。该检查未出现诸如肠穿孔或需要输血的大出血等严重并发症。腺瘤性息肉的患病率有随年龄增加的趋势。在患有息肉的受试者中,72.1%的受试者有远端息肉,根据远端检查结果,与未发现腺瘤性息肉相比,近端息肉患腺瘤性息肉的相对风险为5.4(95%可信区间:4.5 - 6.3),患进展性腺瘤的相对风险为5.1(95%可信区间3.6 - 7.0)。

结论

由经验丰富的结肠镜检查医师进行的结肠镜检查作为一种筛查试验,对于检测患有结直肠息肉的受试者是可行的。

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