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立体定向放射外科治疗癫痫。

Stereotactic radiosurgery for treatment of epilepsy.

作者信息

Quigg Mark, Barbaro Nicholas M

机构信息

Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA.

出版信息

Arch Neurol. 2008 Feb;65(2):177-83. doi: 10.1001/archneurol.2007.40.

Abstract

Stereotactic radiosurgery, known for efficacy in the noninvasive treatment of tumors or arteriovenous malformations that are otherwise difficult to access through traditional surgery, is an emerging technology in the treatment of focal epileptic lesions. Recent studies in the treatment of hypothalamic hamartoma and mesial temporal lobe epilepsy further suggest that seizures in these medically intractable syndromes remit at clinically significant rates with stereotactic radiosurgery. Further studies will be required to determine whether efficacy attains that of traditional surgery while offering a noninvasive technique with potentially lower morbidity.

摘要

立体定向放射外科以其在无创治疗肿瘤或动静脉畸形方面的疗效而闻名,这些肿瘤或畸形通过传统手术难以触及,它是治疗局灶性癫痫病灶的一项新兴技术。最近关于下丘脑错构瘤和内侧颞叶癫痫治疗的研究进一步表明,立体定向放射外科治疗这些药物难治性综合征时,癫痫发作缓解率具有临床显著性。还需要进一步研究以确定其疗效是否能达到传统手术的水平,同时提供一种潜在发病率更低的无创技术。

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