Altenburger Markus Jörg, Schirrmeister Jörg Fabian, Wrbas Karl-Thomas, Hellwig Elmar
Department of Operative Dentistry and Periodontology, Dental School and Hospital, Albert-Ludwigs University Freiburg, Hugstetter Str. 49, 79095 Freiburg, Germany.
Am J Dent. 2007 Dec;20(6):385-9.
To evaluate remineralization and fluoride uptake of demineralized enamel specimens in artificial interproximal spaces using a 250 ppm fluoride mouthrinse (100 ppm amine fluoride and 150 ppm sodium fluoride) compared to a placebo-mouthrinse.
This was a two-way, double-blind, in situ study. 24 volunteers wore intraoral appliances in the lower jaw with mounted demineralized enamel specimens forming an artificial interproximal space. The volunteers rinsed their mouths for 28 days, twice a day with the respective mouthrinse and brushed their teeth at least twice a day with a fluoride-free dentifrice. The specimens were cleaned once a day to simulate the use of dental floss. For analysis methods transversal microradiography, fluoride content measurement and quantitative light-induced fluorescence were used.
Mineral gain was significantly higher after the use of the fluoride mouthrinse: 571.88 Vol.% x microm (+/- 79.33 Vol.% x microm SEM) compared to the placebo treatment 51.14 Vol.% x microm (+/- 72.14 Vol.% x microm SEM). Significantly more fluoride uptake was observed after using the fluoride mouthrinse: 3666.39 microg/cm3 (+/- 513.50 microg/cm3 SEM) than after the placebo mouthrinse: 516.95 microg/cm3 (+/- 75.83 microg/cm3 SEM). The quantitative light-induced fluorescence showed a significant remineralizing effect after the fluoride treatment: -388.47 % x mm2 (+/- 18.76% x mm2 SEM) compared to the placebo treatment -27.88% x mm2 (+/- 20.19% x mm2 SEM).
使用250 ppm含氟漱口水（100 ppm氟化胺和150 ppm氟化钠）与安慰剂漱口水相比，评估人工邻面间隙中脱矿釉质标本的再矿化和氟摄取情况。
这是一项双向、双盲的原位研究。24名志愿者在下颌佩戴口腔装置，装置上安装有脱矿釉质标本，形成人工邻面间隙。志愿者每天用相应的漱口水漱口两次，持续28天，并且每天至少用不含氟的牙膏刷牙两次。标本每天清洁一次以模拟使用牙线的情况。分析方法采用横向显微放射照相、氟含量测量和定量光诱导荧光。
使用含氟漱口水后矿物质增加显著更高：571.88体积%×微米（±79.33体积%×微米标准误），而安慰剂治疗为51.14体积%×微米（±72.14体积%×微米标准误）。使用含氟漱口水后观察到的氟摄取显著更多：3666.39微克/立方厘米（±513.50微克/立方厘米标准误），高于安慰剂漱口水：516.95微克/立方厘米（±75.83微克/立方厘米标准误）。定量光诱导荧光显示氟治疗后有显著的再矿化效果：-388.47%×平方毫米（±18.76%×平方毫米标准误），而安慰剂治疗为-27.88%×平方毫米（±20.19%×平方毫米标准误）。
