Fuenmayor-M Carmen Elena, García-R Maryori, Gómez Denis, Quintiliani-Gamboa María, Altamiranda Cleyzer
Unidad de Anatomía Patológica, Instituto Autónomo Hospital Universidad de los Andes, Mérida, Venezuela.
Invest Clin. 2007 Dec;48(4):509-14.
Extragonadal teratomas are more frequent in the mediastinum and sacrococcygeal region. In this work, two cases of mature mediastinal teratoma, that simulated infection processes are reported. These cases appeared during the last semester of the year 2000 and represent the casuistry of the University Hospital of The Andes (IAHULA) between 1996 and 2005. Two patients, one ten-year-old and the other eight-month-old were admitted at the hospital with a diagnosis of bronchopneumonia and pulmonary abscess with clinical manifestations of cough, dyspnea and chest pain. During surgery, a multicystic tumor composed of fat, sebaceous and mucinous materials, hair, mineralized elements and blood was found in both cases. A histological examination revealed the presence of neoplastic cells derived from more than one germinal strata. Teratomas are infrequent, but the diagnosis must be considered in children with respiratory symptoms. A full histological examination was required to reach a definitive diagnosis. The histological diagnosis was easily performed by conventional light microscopic examination. No additional techniques were necessary. Surgical resection should thus be the first choice for treatment. Four years later, there is no evidence of tumor recurrence.
性腺外畸胎瘤在纵隔和骶尾部区域更为常见。在本研究中,报告了两例模拟感染过程的成熟纵隔畸胎瘤病例。这些病例出现在2000年下半年,代表了1996年至2005年间安第斯大学医院(IAHULA)的病例情况。两名患者,一名10岁,另一名8个月大,因咳嗽、呼吸困难和胸痛等临床表现,以支气管肺炎和肺脓肿的诊断入院。手术中,两例均发现一个由脂肪、皮脂和黏液物质、毛发、矿化成分及血液组成的多囊性肿瘤。组织学检查显示存在源自多个生发层的肿瘤细胞。畸胎瘤并不常见,但对于有呼吸道症状的儿童必须考虑其诊断。需要进行全面的组织学检查以做出明确诊断。通过常规光学显微镜检查很容易进行组织学诊断。无需其他技术。因此,手术切除应作为首选治疗方法。四年后,没有肿瘤复发的迹象。