Al-Quds university, Jerusalem, Palestine.
Palestine Medical Complex (PMC), Ramallah, Palestine.
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241274510. doi: 10.1177/23247096241274510.
Mediastinal mature cystic teratomas are rare benign germ cell tumors that predominantly affect children. Despite their low incidence, they present unique diagnostic and management challenges. Early recognition and appropriate surgical intervention are crucial for optimal outcomes. This case report aims to highlight the importance of prompt diagnosis and management of mediastinal mature cystic teratomas in pediatric patients. We present the case of a 10-year-old female patient who presented with persistent chest pain and dyspnea. Imaging studies, including a chest X-ray and contrast-enhanced chest CT scan, revealed a large, well-circumscribed anterior mediastinal mass with calcifications. The patient underwent a right thoracotomy, resulting in the excision of a 6 × 5 × 5 cm mature cystic teratoma. Histopathological examination confirmed the diagnosis. The patient had an uneventful recovery and was discharged in stable condition. Mediastinal mature cystic teratomas pose diagnostic challenges due to their nonspecific symptoms and heterogeneous imaging characteristics. Differential diagnosis includes other mediastinal masses containing fat and calcifications. Surgical excision is the preferred treatment, although complete removal can be challenging due to adhesions to neighboring structures. Close follow-up is necessary to monitor for recurrence and complications. Mediastinal mature cystic teratomas are rare tumors with variable clinical presentations. Early detection and surgical intervention are crucial for optimal outcomes. These tumors should be included in the list of differential diagnoses for mediastinal masses in pediatric patients.
纵隔成熟囊性畸胎瘤是罕见的良性生殖细胞肿瘤，主要影响儿童。尽管其发病率低，但它们具有独特的诊断和管理挑战。早期识别和适当的手术干预对于获得最佳结果至关重要。本病例报告旨在强调及时诊断和管理儿科纵隔成熟囊性畸胎瘤的重要性。我们报告了一例 10 岁女性患者，其主要表现为持续性胸痛和呼吸困难。影像学研究，包括胸部 X 光和增强胸部 CT 扫描，显示出一个大的、边界清楚的前纵隔肿块，伴有钙化。患者接受了右开胸术，切除了一个 6×5×5cm 的成熟囊性畸胎瘤。组织病理学检查证实了诊断。患者恢复顺利，情况稳定出院。纵隔成熟囊性畸胎瘤由于其非特异性症状和异质性的影像学特征，给诊断带来了挑战。鉴别诊断包括其他含有脂肪和钙化的纵隔肿块。手术切除是首选治疗方法，但由于与邻近结构的粘连，完全切除可能具有挑战性。需要密切随访以监测复发和并发症。纵隔成熟囊性畸胎瘤是一种罕见的肿瘤，具有不同的临床表现。早期发现和手术干预对于获得最佳结果至关重要。这些肿瘤应列入儿科纵隔肿块的鉴别诊断列表中。
