Sütterlin H, Alexy R, Kümmerer K
Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Hugstetter Street 55, 79106 Freiburg, Germany.
Ecotoxicol Environ Saf. 2008 Oct;71(2):498-505. doi: 10.1016/j.ecoenv.2007.12.015. Epub 2008 Feb 12.
Mixtures of chemicals are present in the aquatic environment but standard testing methods assess only single compounds. One aspect of this question is the importance of the formation of ionic pairs, for example from quaternary ammonium compounds with organic anions, and the significance of the ionic pairs for bacterial toxicity in the aquatic environment. The aim of the present study was to investigate the toxicity of the cationic quaternary ammonium compound benzalkonium chloride (BAC) against aquatic bacteria in the presence of substances commonly found in wastewater, such as the anionic surfactant linear alkylbenzene sulfonate (LAS), naphthalene sulfonic acid (NSA), sodium dodecylsulfonate (SDS), and benzene sulfonic acid (BSA). The growth inhibition test with Pseudomonas putida and the Vibrio fischeri luminescent inhibition test were used to determine the toxicity of single compounds and compound mixtures. The results found in this study indicate that ion pair formation is of minor significance under the test conditions applied here.
化学物质混合物存在于水生环境中，但标准测试方法仅评估单一化合物。这个问题的一个方面是离子对形成的重要性，例如由季铵化合物与有机阴离子形成的离子对，以及这些离子对在水生环境中对细菌毒性的意义。本研究的目的是调查阳离子季铵化合物苯扎氯铵（BAC）在废水常见物质存在下对水生细菌的毒性，这些物质如阴离子表面活性剂直链烷基苯磺酸盐（LAS）、萘磺酸盐（NSA）、十二烷基磺酸钠（SDS）和苯磺酸盐（BSA）。使用恶臭假单胞菌生长抑制试验和费氏弧菌发光抑制试验来确定单一化合物和化合物混合物的毒性。本研究的结果表明，在所应用的测试条件下，离子对形成的意义不大。
