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泰国陆军医科学生和护理专业学生甲型肝炎血清流行率:区域风险差异的反映

Seroprevalence of hepatitis A in thai army medical cadets and nursing students: a reflection of regional risk differences.

作者信息

Samakoses Rudiwilai, Myint Khin Saw Aye, Rangsin Ram, Areekul Wirote, Kerdpanich Angkool, Watanaveeradej Veerachai, Mammen Mammen P

机构信息

Department of Pediatrics, RTA Medical Department, Phramongkutklao Hospital, Rajavithi Bangkok 10400, Thailand.

出版信息

Mil Med. 2007 Dec;172(12):1275-8. doi: 10.7205/milmed.172.12.1275.

DOI:10.7205/milmed.172.12.1275
PMID:18274028
Abstract

A cross-sectional study of 432 army college students comprising 278 medical cadets and 154 nursing students, ages ranging from 15 to 26 years, was conducted in 2001 to determine the seroprevalence of hepatitis A virus (HAV) antibody. Serum specimens were tested for HAV antibody by a commercial enzyme immunoassay method. Anti-HAV was detected in 14.0%, 17.5%, and 15.3% of medical cadets, nursing students, and the total cohort, respectively. There was no statistically significant difference in seroprevalence between medical cadets and nursing students. Increasing prevalence of HAV correlated with increasing age. Significantly higher seroprevalence was detected in students from provinces outside of Bangkok compared to those who were from Bangkok (18.7% vs. 9.8%). The highest HAV seroprevalence was observed in subjects from the northeastern region of Thailand, suggesting that this region may be associated with greater risk for infection and should be the focus of preventive health strategies.

摘要

2001年对432名年龄在15至26岁之间的军校学生进行了一项横断面研究,其中包括278名医学学员和154名护理专业学生,以确定甲型肝炎病毒(HAV)抗体的血清流行率。采用商业酶免疫测定法检测血清标本中的HAV抗体。医学学员、护理专业学生和整个队列中抗-HAV的检出率分别为14.0%、17.5%和15.3%。医学学员和护理专业学生之间的血清流行率没有统计学上的显著差异。HAV流行率的增加与年龄的增长相关。与来自曼谷的学生相比,来自曼谷以外省份的学生血清流行率显著更高(18.7%对9.8%)。在泰国东北部地区的受试者中观察到最高的HAV血清流行率,这表明该地区可能与更高的感染风险相关,应成为预防性健康策略的重点。

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