血糖试纸在肾衰竭患者中是否可靠？

Are blood glucose reagent strips reliable in renal failure?

作者信息

Clark J D, Goldberg L, Jones K, Hartog M

机构信息

Department of Medicine, Southmead Hospital, Bristol, UK.

出版信息

Diabet Med. 1991 Feb-Mar;8(2):168-71. doi: 10.1111/j.1464-5491.1991.tb01565.x.

DOI:10.1111/j.1464-5491.1991.tb01565.x

PMID:1827404

Abstract

In vitro studies have suggested that a low packed cell volume may cause reagent strips to overestimate blood glucose concentration. The reliability of such strips has therefore been investigated in diabetic patients with end-stage renal failure, all of whom had low haematocrits (24 +2- 4 (4/- SD) %). Three brands of strips were evaluated and their results were compared with laboratory whole blood glucose concentrations determined on the same samples. All over-read compared with the laboratory (BM Glycemie 1-44 strips 118 +/- 1%, Glucostix 132 +/- 2%, ExacTech strips 163 +/- 4%) and the percentage overread was negatively correlated with the haematocrit for each strip (all p less than 0.001).

摘要

体外研究表明，低红细胞压积可能会导致试纸条高估血糖浓度。因此，研究了这类试纸条在终末期肾衰竭糖尿病患者中的可靠性，这些患者的血细胞比容均较低（24±2 - 4（4 / -标准差）%）。对三个品牌的试纸条进行了评估，并将其结果与在相同样本上测定的实验室全血葡萄糖浓度进行比较。与实验室结果相比，所有试纸条均存在读数偏高的情况（BM Glycemie 1 - 44试纸条为118±1%，Glucostix试纸条为132±2%，ExacTech试纸条为163±4%），且每条试纸条的读数偏高百分比与血细胞比容呈负相关（所有p均小于0.001）。