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糖尿病患者的间歇性腹膜慢性透析:该技术对透析过程中血糖及蛋白质丢失的影响

[Intermittent peritoneal chronic dialysis in diabetic patients: effect of the technique on blood glucose and protein loss during the procedure].

作者信息

García Ortiz R, Gómez M, Olea C

出版信息

Rev Med Chil. 1989 Dec;117(12):1367-73.

PMID:2519375
Abstract

We performed a prospective study in 4 diabetic (one insulin dependent) patients with end stage chronic renal disease, in whom intermittent peritoneal dialysis was performed with and without addition of insulin to the dialysate. Plasma levels of glucose and insulin were compared to those obtained in 5 non-diabetic controls. With no insulin added, absolute changes in glucose and insulin from predialysis levels were similar in diabetics and non-diabetics. The addition of insulin to the dialysate did not modify nitrogen losses through the peritoneal membrane. The absorption of glucose from the dialysate fluid in the presence of insulin was greater in diabetics than in non-diabetic patients (p less than 0.01).

摘要

我们对4例患有终末期慢性肾病的糖尿病患者(其中1例为胰岛素依赖型)进行了一项前瞻性研究,这些患者在透析液中添加胰岛素和不添加胰岛素的情况下进行间歇性腹膜透析。将糖尿病患者的血糖和胰岛素血浆水平与5名非糖尿病对照者的水平进行比较。在不添加胰岛素的情况下,糖尿病患者和非糖尿病患者透析前水平的葡萄糖和胰岛素的绝对变化相似。向透析液中添加胰岛素并未改变通过腹膜的氮损失。在有胰岛素存在的情况下,糖尿病患者从透析液中吸收的葡萄糖比非糖尿病患者更多(p<0.01)。

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