肾移植活检中KIM-1的表达：改进金标准。

KIM-1 expression in kidney allograft biopsies: Improving the gold standard.

作者信息

Abulezz S

机构信息

University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

出版信息

Kidney Int. 2008 Mar;73(5):522-3. doi: 10.1038/sj.ki.5002772.

DOI:10.1038/sj.ki.5002772

PMID:18274540

Abstract

Long-term outcomes of kidney allografts have shown only marginal improvement over the last three decades, despite the remarkable improvement in acute rejection and one-year graft survival. Novel biomarkers of tubular injury may prevent irreversible damage to the tubulointerstitial compartment and improve allograft survival.

摘要

尽管在急性排斥反应和移植肾一年生存率方面有显著改善，但在过去三十年中，同种异体肾移植的长期结果仅显示出轻微改善。肾小管损伤的新型生物标志物可能预防肾小管间质部分的不可逆损伤，并提高移植肾的生存率。