铑催化的烯烃脱氢硼化反应：通过C-H活化生成硼酸乙烯酯。
Rhodium catalysed dehydrogenative borylation of alkenes: vinylboronates via C-H activation.
作者信息
Mkhalid Ibraheem A I, Coapes R Benjamin, Edes S Natasha, Coventry David N, Souza Fabio E S, Thomas Rhodri Ll, Hall Jonathan J, Bi Si-Wei, Lin Zhenyang, Marder Todd B
机构信息
Department of Chemistry, Durham University, Durham, UK.
出版信息
Dalton Trans. 2008 Feb 28(8):1055-64. doi: 10.1039/b715584k. Epub 2007 Dec 20.
We present herein a high yield, highly selective catalytic synthesis of vinylboronate esters (VBEs), including 1,1-disubstituted VBEs, from alkenes without significant hydrogenation or hydroboration, using the simple catalyst precursor, trans-[RhCl(CO)(PPh3)2] (1), and the diboron reagents B2pin2 (2a, pin = pinacolato = OCMe2CMe2O) or B2neop2 (2b, neop = neopentylglycolato = OCH2CMe2CH2O), or the monoboron reagent HBpin, all of which are commercially available. The reactions were conducted at 80 degrees C using conventional heating, or in a microwave reactor at 150 degrees C.
我们在此展示了一种高产率、高选择性的催化合成乙烯基硼酸酯（VBEs）的方法，包括1,1 - 二取代的VBEs，该方法以简单的催化剂前体反式 - [RhCl(CO)(PPh3)2]（1）和二硼试剂B2pin2（2a，pin = 频哪醇酯 = OCMe2CMe2O）或B2neop2（2b，neop = 新戊二醇酯 = OCH2CMe2CH2O），或单硼试剂HBpin为原料，在不发生显著氢化或硼氢化反应的情况下，从烯烃合成VBEs，所有这些试剂均可商购获得。反应在80摄氏度下使用传统加热方式进行，或在微波反应器中于150摄氏度下进行。
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